Empyema is a serious health problem that can affect individuals of all ages. Although there has been some change in treatment modalities with the advancement of technology, there is still no standard approach to treatment. The most common cause of parapneumonic empyema is parapneumonic or postpneumonic effusions. Inappropriate diagnosis and intervention can result in chronic parapneumonic empyema. This can lead to pleural thickening, which can further reduce lung and thorax volume and impair respiratory function. In more advanced cases, more invasive surgical procedures may be needed, such as thoracotomy and decortication. Alternatively, myoplasty or thoracomyplasty may be employed. As the main principle in empyema treatment is to match the stage, early diagnosis and intervention are crucial. Consequently, the primary objective is to administer appropriate antibiotics, perform appropriate drainage, and, in cases of loculation, implement early debridement (fibrinolytic therapy, VATS) in order to reduce the necessity for thoracotomy.n