Release Date: 2024-02-12

Gene Therapy in Heart Diseases

Veysi Akpolat (Author), Osman Ozdabakoglu (Author)

Release Date: 2024-02-12

Heart diseases are one of the most important health problems of our time. New and effective methods are constantly sought for the treatment of these diseases, In this book chapter, we will examine the potential and current status of gene therapy in heart diseases. First, we will cover basic concepts for understanding the genetic basis [...]

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    Work TypeBook Chapter
    Published inGene Therapy
    First Page107
    Last Page117
    DOIhttps://doi.org/10.69860/nobel.9786053358824.7
    Page Count11
    Copyright HolderNobel Tıp Kitabevleri
    Licensehttps://nobelpub.com/publish-with-us/copyright-and-licensing
    Heart diseases are one of the most important health problems of our time. New and effective methods are constantly sought for the treatment of these diseases, In this book chapter, we will examine the potential and current status of gene therapy in heart diseases. First, we will cover basic concepts for understanding the genetic basis of heart disease and how gene therapy works. Next, we will discuss the results of current research and clinical studies and future directions. Finally, we will evaluate the potential of gene therapy in the treatment of heart diseases and the challenges ahead.

    Veysi Akpolat (Author)
    Professor, Dicle University
    https://orcid.org/0000-0002-2435-7800
    3Veysi Akpolat, currently works as a professor at Dicle University, Department of Biophysics. He graduated from Dicle University Faculty of Medicine with the title of Medical Doctor in 1990. Later, he completed his doctorate in the biophysics department of Dicle University Faculty of Medicine in 2004. He has many research and projects on cell biophysics. The areas he is most interested in are ion channels diseases, electromagnetic field cell interactions, electrophysiological biopotentials, osteoporosis, artificial intelligence and its use in medicine.

    Osman Ozdabakoglu (Author)
    MD, Specialist Doctor, Private Acıbadem Bursa Hospital
    https://orcid.org/0000-0002-2837-3015
    3Osman Özdabakoğlu, currently works as a specialist cardiologist at Acıbadem Hospital. I graduated from Kocaeli University Faculty of Medicine with the title of Medical Doctor in 2005. in 2010, I became a cardiologist. I have many research and projects on heart diseases. The areas I am most interested in are heart failure , coronary heart diseases, invazive treatment.

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    • https://www.nhlbi.nih.gov/health/genetic-therapies/types

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    • Rasmussen, H.S., Rasmussen, C.S., Macko, J.: VEGF gene therapy for coronary artery disease and peripheral vascular disease. Cardiovasc Radiat Med 2002: 3(2); 114-117.

    • Hajjar, R.J., Hug, F., Matsui, T., Rosensueing, A.: Genetic editing of dysfunctional myocardium. Med. Clin. North. Am. 2003: 87(2); 553-67.

    • Vora N., Patel P., Gajjar A., et. al. Gene therapy for heart failure: A novel treatment for the age old disease. Disease-a-Month Volume 70, Issue 2, February 2024, 101636.

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