In the emergency department (ED), prompt diagnosis and treatment of diabetic foot complications are critical to prevent severe outcomes such as infections and amputations. Clinical assessment should include careful examination for signs of infection, neuropathy, and vascular compromise. Immediate management involves wound care, debridement if necessary, and empirical antibiotic therapy based on the likely pathogens. Ensuring adequate glycemic control and addressing underlying vascular issues are integral parts of treatment. Early involvement of multidisciplinary teams including podiatrists and infectious disease specialists can optimize outcomes and reduce the risk of further complications in diabetic foot emergencies.