Nutraceutical Use in Migraine
Ahmet Dundar (Author), Hasan Huseyin Ozdemir (Author)
Release Date: 2024-05-31
Migraine is a primary episodic headache disorder that is variously accompanied by neurological, gastrointestinal and autonomic changes. It is one of the most common neurological diseases that causes loss of employment, especially in young people. In migraine treatment, it is necessary to avoid triggering factors and reduce the frequency, duration and severity of attacks. Treatment [...]
Media Type
Buy from
Price may vary by retailers
Work Type | Book Chapter |
---|---|
Published in | Brain Health and Medicinal Plants |
First Page | 245 |
Last Page | 265 |
DOI | https://doi.org/10.69860/nobel.9786053359241.12 |
Page Count | 21 |
Copyright Holder | Nobel Tıp Kitabevleri |
License | https://nobelpub.com/publish-with-us/copyright-and-licensing |
Ahmet Dundar (Author)
Associate Professor, Mardin Artuklu University
https://orcid.org/0000-0003-0527-189X
3Dr.Ahmet DÜNDAR works as an Associate Professor at Mardin Artuklu University Vocational School of Health Services, Department of Medical Services and Techniques. He received his undergraduate degree from Yüzüncü Yıl University, Faculty of Science. He continued his master’s and doctorate degrees at the same university’s Institute of Health Sciences, Faculty of Medicine, Department of Medical Biochemistry. In 2014, he started working as an assistant professor at Dicle Health Services Vocational School, Department of Medical Services and Techniques. In 2018, he was appointed as a faculty member at Mardin Artuklu University, Vocational School of Health Services, Department of Medical Services and Techniques. His main research areas include antioxidants, oxidative stress, vitamins, inflammation, biochemical evaluation of neurological diseases and molecular genetics. He graduated 2 MSc students. He has completede 4 projects.
Hasan Huseyin Ozdemir (Author)
MD,Associate Professor , Private Ataköy Hospital
https://orcid.org/0000-0003-1753-1046
3He was born in Kahramanmaraş in 1982. He completed his primary and secondary education in K. Maraş. He received the title of Associate Professor in 2015. He has many studies in international and national journals and meetings. He speaks intermediate English and German.
Zarifoglu M, Siva A, Hayran O. the Turkish headache epidemiology study group. An epidemiological study of headache in Turkey: a nationwide survey. Neurology 1998; 50(suppl 4):80-85.
Lay CL, Broner SW. "Migraine in women". Neurologic Clinics. 27 (2). 503-11
Stovner LJ, Zwart JA, Hagen K, Terwindt GM, Pascual J (Nisan 2006). "Epidemiology of headache in Europe". European Journal of Neurology. 13(4). 333-45.
Moskowitz MA. Neurogenic inflammation in the pathophysiology and treatment of migraine. Neurology 1993; 43(Suppl 3):16-20.
Reuter U, Bolay H, Jansen-Olesen I, Chiarugi A, Sanchez del Rio M, Letourneau R, et al. Delayed inflammation in rat meninges: implications for migraine pathophysiology. Brain 2001; 124:2490-502.
Burstein R, Noseda R, Borsook D. Migraine: multiple processes, complex pathophysiology. J Neurosci. 2015 Apr 29;35(17):6619-29.
Mollaoğlu M. Trigger factors in migraine patients. J Health Psychol. 2013 Jul;18(7):984-94.
van Casteren DS, Verhagen IE, Onderwater GL, MaassenVanDenBrink A, Terwindt GM. Sex differences in prevalence of migraine trigger factors: A cross-sectional study. Cephalalgia. 2021 May;41(6):643-648.
Sun-Edelstein C, Mauskop A. Foods and supplements in the management of migraine headaches. Clin J Pain. 2009 Jun;25(5):446-52.
Hauge AW, Kirchmann M, Olesen J. Characterization of consistent triggers of migraine with aura. Cephalalgia. 2011;31:416‐438
Hindiyeh NA, Zhang N, Farrar M, Banerjee P, Lombard L, Aurora SK. The Role of Diet and Nutrition in Migraine Triggers and Treatment: A Systematic Literature Review. Headache. 2020 Jul;60(7):1300-1316.
Omer Saglam UK, Engin D, Bilal C, Nergis C, Aytug A.The role of lifestyle modifications in the management of migraine associated vertigo. J Clin Anal Med. 2015;6:763‐765.
Tepper SJ, Stillman MJ. What is the best drug-delivery approach for the acute treatment of migraine? Expert Rev Neurother 2012;12(3):253–5.
Burch R. Acute Treatment of Migraine. Continuum (Minneap Minn). 2024 Apr 1;30(2):344-363.
Pascual J, Panni T, Dell'Agnello G, Gonderten S, Novick D, Evers S. Preventive treatment patterns and treatment satisfaction in migraine: results of the OVERCOME (EU) study. J Headache Pain. 2023 Jul 17;24(1):88.
Puri V, Nagpal M, Singh I, Singh M, Dhingra GA, Huanbutta K, Dheer D, Sharma A, Sangnim T. A Comprehensive Review on Nutraceuticals: Therapy Support and Formulation Challenges. Nutrients. 2022 Nov 3;14(21):4637.
Puledda F, Shields K. Non-Pharmacological Approaches for Migraine. Neurotherapeutics. 2018 Apr;15(2):336-345.
G, Suzuki S, Morishita N, Takeshita M, Kanou K, Takamatsu T, Morichi S, Ishida Y, Watanabe Y, Go S, Oana S, Kawashima H. Experimental and Clinical Evidence of the Effectiveness of Riboflavin on Migraines. Nutrients. 2021 Jul 29;13(8):2612.
Hoenen J, Jacquy J, Lenaerts M. Effectiveness of high-dose riboflavin in migraine prophylaxis A randomized controlled trial. Neurology. 1998;50(2):466–70.
MacLennan SC, Wade FM, Forrest KM, Ratanayake PD, Fagan E, Antony J. High-dose riboflavin for migraine prophylaxis in children: a double-blind, randomized, placebo-controlled trial. Journal of child neurology. 2008;23(11):1300–4.
Athaillah A, Dimyati Y, Saing JH, Saing B, Hakimi H, Lelo A. Riboflavin as migraine prophylaxis in adolescents. 30Jun.2012;52(3):132-7
Nambiar N.J., Aiyappa C., Srinivasa R. Oral riboflavin versus oral propranolol in migraine prophylaxis: An open label randomized controlled trial. Neurol. Asia. 2011;16:223–229.
Gaul C, Diener HC, Danesch U; Migravent® Study Group. Improvement of migraine symptoms with a proprietary supplement containing riboflavin, magnesium and Q10: a randomized, placebo-controlled, double-blind, multicenter trial. J Headache Pain. 2015;16:516.
Yamanaka G, Suzuki S, Morishita N, Takeshita M, Kanou K, Takamatsu T, Morichi S, Ishida Y, Watanabe Y, Go S, Oana S, Kawashima H. Experimental and Clinical Evidence of the Effectiveness of Riboflavin on Migraines. Nutrients. 2021 Jul 29;13(8):2612.
MacLennan S.C., Wade F.M., Forrest K.M., Ratanayake P.D., Fagan E., Antony J. High-dose riboflavin for migraine prophylaxis in children: A double-blind, randomized, placebo-controlled trial. J. Child Neurol.2008;23:1300–1304.
Dolati S, Rikhtegar R, Mehdizadeh A, Yousefi M. The Role of Magnesium in Pathophysiology and Migraine Treatment. Biol Trace Elem Res. 2020 Aug;196(2):375-383.
de Baaij JH, Hoenderop JG, Bindels RJ. Magnesium in man: implications for health and disease. Physiol Rev. 2015 Jan;95(1):1-46.
Fila M., Chojnacki C., Chojnacki J., Blasiak J. Nutrients to Improve Mitochondrial Function to Reduce Brain Energy Deficit and Oxidative Stress in Migraine. Nutrients. 2021;13:4433.
Chiu HY, Yeh TH, Huang YC, Chen PY. Effects of Intravenous and Oral Magnesium on Reducing Migraine: A Meta-analysis of Randomized Controlled Trials. Pain Physician. 2016 Jan;19(1):E97-112.
Von Luckner A, Riederer F. Magnesium in Migraine Prophylaxis-Is There an Evidence-Based Rationale? A Systematic Review. Headache. 2018 Feb;58(2):199-209.
Köseoglu E, Talaslioglu A, Gönül AS, Kula M. The effects of magnesium prophylaxis in migraine without aura. Magnes Res. 2008 Jun;21(2):101-8
Sood B, Patel P, Keenaghan M. Coenzyme Q10. 2024 Jan 30. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan–.
Sazali S, Badrin S, Norhayati MN, Idris NS. Coenzyme Q10 supplementation for prophylaxis in adult patients with migraine-a meta-analysis. BMJ Open. 2021 Jan 5;11(1):e039358.
Shoeibi A, Olfati N, Soltani Sabi M, Salehi M, Mali S, Akbari Oryani M. Effectiveness of coenzyme Q10 in prophylactic treatment of migraine headache: an open-label, add-on, controlled trial. Acta Neurol Belg. 2017 Mar;117(1):103-109.
Parohan M, Sarraf P, Javanbakht MH, Ranji-Burachaloo S, Djalali M. Effect of coenzyme Q10 supplementation on clinical features of migraine: a systematic review and dose-response meta-analysis of randomized controlled trials. Nutr Neurosci. 2020 Nov;23(11):868-875.
Visser EJ, Drummond PD, Lee-Visser JLA. Reduction in Migraine and Headache Frequency and Intensity With Combined Antioxidant Prophylaxis (N-acetylcysteine, Vitamin E, and Vitamin C): A Randomized Sham-Controlled Pilot Study. Pain Pract. 2020 Sep;20(7):737-747.
Shaik MM, Gan SH. Vitamin supplementation as possible prophylactic treatment against migraine with aura and menstrual migraine. Biomed Res Int. 2015;2015:469529.
Bali L, Callaway E. Vitamin C and migraine: a case report. N Engl J Med. 1978 Aug 17;299(7):364.
Moghadamtousi SZ, Kadir HA, Hassandarvish P, Tajik H, Abubakar S, Zandi K. A review on antibacterial, antiviral, and antifungal activity of curcumin. Biomed Res Int. 2014;2014:186864.
S.Hassanizadeh, M.Shojaei, M.Bagherniya,A.N.Orekhov,A.Sahebkar Effect of nano-curcumin on various diseases: a comprehensive review of clinical trials Biofactors (2023)
Heidari H, Shojaei M, Askari G, Majeed M, Bagherniya M, Barreto GE, Sahebkar A. The impact of curcumin on migraine: A comprehensive review. Biomed Pharmacother. 2023 Aug;164:114910.
A.E.Bulboacă,S.D.Bolboacă,I.C.Stănescu,C.A.Sfrângeu,A.Porfire,L.Tefas,et al. The effect of intravenous administration of liposomal curcumin in addition to sumatriptan treatment in an experimental migraine model in rats Int. J. Nanomed.,13(2018), p.3093
A.E.Bulboacă,S.D.Bolboacă, I.C.Stănescu, C.A.Sfrângeu, A.C. Bulboacă Preemptive analgesic and antioxidative effect of curcumin for experimental migraine BioMed. Res. Int.,2017
M. Sedighiyan, M. Abdolahi, E. Jafari, Z. Vahabi, S. Sohrabi Athar, S. Hadavi, et al. The effects of nano-curcumin supplementation on adipokines levels in obese and overweight patients with migraine: a double blind clinical trial study BMC Res. Notes, 15(1) (2022), pp. 1-7
M. Parohan, P. Sarraf, M.H. Javanbakht, A.R. Foroushani, S. Ranji-Burachaloo, M. Djalali The synergistic effects of nano-curcumin and coenzyme Q10 supplementation in migraine prophylaxis: a randomized, placebo-controlled, double-blind trial Nutr. Neurosci., 24 (4) (2021), pp. 317-326
Kim M.S., Bang J.H., Lee J., Han J.S., Baik T.G., Jeon W.K. Ginkgo biloba L. extract protects against chronic cerebral hypoperfusion by modulating neuroinflammation and the cholinergic system. Phytomedicine. 2016;23:1356–1364.
Choi, M.S.; Kim, J.K.; Kim, D.H.; Yoo, H.H. Effects of gut microbiota on the bioavailability of bioactive compounds from ginkgo leaf extracts.Metabolites 2019,9, 132.
J.; Shah, Z.A. Ginkgo biloba prevents transient global ischemia-induced delayed hippocampal neuronal death through antioxidant and anti-inflammatory mechanism.Neurochem. Int.2013,62, 189–197.
Gutowska I, Baranowska-Bosiacka I, Barczak K, Chlubek D. The Use of Antioxidants in the Treatment of Migraine. Antioxidants (Basel). 2020 Jan 28;9(2):116.
Allais G, D'Andrea G, Maggio M, Benedetto C. The efficacy of ginkgolide B in the acute treatment of migraine aura: an open preliminary trial. Neurol Sci. 2013 May;34 Suppl 1:S161-3.
Esposito M, Carotenuto M. Ginkgolide B complex efficacy for brief prophylaxis of migraine in school-aged children: an open-label study. Neurol Sci. 2011 Feb;32(1):79-81.
Usai S, Grazzi L, Andrasik F, Bussone G. An innovative approach for migraine prevention in young age: a preliminary study. Neurol Sci. 2010 Jun;31 Suppl 1(Suppl 1):S181-3.
Rebouche CJ: Kinetics, pharmacokinetics, and regulation of L-carnitine and acetyl-L-carnitine metabolism. Ann N Y Acad Sci. 2004, 1033: 30-41.
L, Yaghini O, Ghazavi M, Aslani N. L-carnitine versus Propranolol for pediatric migraine prophylaxis. Iran J Child Neurol. 2021 Spring;15(2):77-86.
Hajihashemi P, Askari G, Khorvash F, Reza Maracy M, Nourian M. The effects of concurrent Coenzyme Q10, L-carnitine supplementation in migraine prophylaxis: A randomized, placebo-controlled, double-blind trial. Cephalalgia. 2019 Apr;39(5):648-654.
Tarighat Esfanjani A, Mahdavi R, Ebrahimi Mameghani M, Talebi M, Nikniaz Z, Safaiyan A. The effects of magnesium, L-carnitine, and concurrent magnesium-L-carnitine supplementation in migraine prophylaxis. Biol Trace Elem Res. 2012 Dec;150(1-3):42-8.
Wang W, Pan D, Liu Q, Chen X, Wang S. L-Carnitine in the Treatment of Psychiatric and Neurological Manifestations: A Systematic Review. Nutrients. 2024 Apr 20;16(8):1232.
Nguyen H, Pellegrini MV, Gupta V. Alpha-Lipoic Acid. 2024 Jan 26. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024
Gross EC, et al. Mitochondrial function and oxidative stress markers in higher-frequency episodic migraine.Sci. Rep.2020;11:1–12.
Kelishadi MR, Naeini AA, Khorvash F, Askari G, Heidari Z. The beneficial effect of Alpha-lipoic acid supplementation as a potential adjunct treatment in episodic migraines. Sci Rep. 2022 Jan 7;12(1):271.
Magis D, et al. A randomized double-blind placebo-controlled trial of thioctic acid in migraine prophylaxis. Headache. 2007;47:52–57.
Ali AM, Awad TG, Al-Adl NM. Efficacy of combined topiramate/thioctic acid therapy in migraine prophylaxis. Saudi Pharm J. 2010 Oct;18(4):239-43.
Ghorbani Z, Togha M, Rafiee P, Ahmadi ZS, Rasekh Magham R, Haghighi S, Razeghi Jahromi S, Mahmoudi M. Vitamin D in migraine headache: a comprehensive review on literature. Neurol Sci. 2019 Dec;40(12):2459-2477.
Ghorbani Z, Rafiee P, Fotouhi A, Haghighi S, Rasekh Magham R, Ahmadi ZS, Djalali M, Zareei M, Razeghi Jahromi S, Shahemi S, Mahmoudi M, Togha M. The effects of vitamin D supplementation on interictal serum levels of calcitonin gene-related peptide (CGRP) in episodic migraine patients: post hoc analysis of a randomized double-blind placebo-controlled trial. J Headache Pain. 2020 Feb 24;21(1):22.
Dell'Isola GB, Tulli E, Sica R, Vinti V, Mencaroni E, Di Cara G, Striano P, Verrotti A. The Vitamin D Role in Preventing Primary Headache in Adult and Pediatric Population. J Clin Med. 2021 Dec 20;10(24):5983.
Ghorbani Z, Togha M, Rafiee P, Ahmadi ZS, Rasekh Magham R, Djalali M, Shahemi S, Martami F, Zareei M, Razeghi Jahromi S, Ariyanfar S, Mahmoudi M. Vitamin D3 might improve headache characteristics and protect against inflammation in migraine: a randomized clinical trial. Neurol Sci. 2020 May;41(5):1183-1192.
Ghorbani, Z.; Togha, M.; Rafiee, P.; Ahmadi, Z.S.; Rasekh Magham, R.; Djalali, M.; Shahemi, S.; Martami, F.; Zareei, M.; Razeghi Jahromi, S.; et al. Vitamin D3 might improve headache characteristics and protect against inflammation in migraine: A randomized clinical trial. Neurol. Sci.2020,41, 1183–1192.
Rajapakse T, Davenport WJ. Phytomedicines in the Treatment of Migraine. CNS Drugs. 2019 May;33(5):399-415.
Pfaffenrath V, Diener HC, Fischer M, Friede M, Henneicke-von Zepelin HH; Investigators. The efficacy and safety of Tanacetum parthenium (feverfew) in migraine prophylaxis--a double-blind, multicentre, randomized placebo-controlled dose-response study. Cephalalgia. 2002 Sep;22(7):523-32.
Rajapakse T, Pringsheim T. Nutraceuticals in migraine: a summary of existing guidelines for use. Headache.2016;56:808–816.
Taylor FR.Nutraceuticals and headache: the biological basis. Headache 2011;51:484-501
Wider B, Pittler MH, Ernst E. Feverfew for preventing migraine. Cochrane Database Syst Rev. 2015 Apr 20;4(4):CD002286.
Vikelis M, Dermitzakis EV, Vlachos GS, Soldatos P, Spingos KC, Litsardopoulos P, Kararizou E, Argyriou AA. Open Label Prospective Experience of Supplementation with a Fixed Combination of Magnesium, Vitamin B2, Feverfew, Andrographis Paniculata and Coenzyme Q10 for Episodic Migraine Prophylaxis. J Clin Med. 2020 Dec 27;10(1):67.
Weerdt CJ, Bootsma HPR, Hendriks H. Herbal medicines in migraine prevention: randomized double-blind placebo-controlled crossover trial of a feverfew preparation.Phytomedicine1996;3:225-30.
Pfaffenrath V, Diener HC, Fischer M, Friede M, Henneicke-von Zeppelin HH. The efficacy and safety of Tanacetum parthenium (feverfew) in migraine prophylaxis -- a double-blind, multicentre, randomized placebo-controlled dose-response study.Cephalalgia2002;22:523-32.
LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012–. Butterbur. 2019 Feb 18.
Borlak J, Diener HC, Kleeberg-Hartmann J, Messlinger K, Silberstein S. Petasites for Migraine Prevention: New Data on Mode of Action, Pharmacology and Safety. A Narrative Review. Front Neurol. 2022 Apr 26;13:864689.
Lipton RB, Gobel H, Einhaupl KM, Wilks K, Mauskop A. Petasites hybridus root (butterbur) is an effective preventive treatment for migraine. Neurology. (2004) 63:2240–4
Lovell BV, Marmura MJ. New therapeutic developments in chronic migraine. Curr Opin Neurol. 2010 Jun;23(3):254-8. doi:
Utterback G, Zacharias R, Timraz S, Mershman D. Butterbur extract: prophylactic treatment for childhood migraines. Complement Ther Clin Pract. 2014 Feb;20(1):61-4.
Delavar Kasmaei H, Ghorbanifar Z, Zayeri F, Minaei B, Kamali SH, Rezaeizadeh H, Amin G, Ghobadi A, Mirzaei Z. Effects of Coriandrum sativum Syrup on Migraine: A Randomized, Triple-Blind, Placebo-Controlled Trial. Iran Red Crescent Med J. 2016 Jan 2;18(1):e20759.
Pathan AR, Kothawade KA, Logade MN. Anxiolytic and analgesic effect of seeds of Coriandrum sativum Linn. Inte J Res Pham Chem. 2011;1(4):1087–99.
Kurt N, Çankaya Tatlı İ. Aromaterapi Uygulamaları ve Uçucu Yağlar Lokman Hekim Dergisi, 2021; 11 (2): 230-241
Murtey P, Noor NM, Ishak A, Idris NS. Essential Oils as an Alternative Treatment for Migraine Headache: A Systematic Review and Meta-Analysis. Korean J Fam Med. 2024 Jan;45(1):18-26.
Yuan R, Zhang D, Yang J, Wu Z, Luo C, Han L, et al. Review of aromatherapy essential oils and their mechanism of action against migraines. J Ethnopharmacol. 2021;265:113326.
onix_3.0::thoth | Thoth ONIX 3.0 |
---|---|
onix_3.0::project_muse | Project MUSE ONIX 3.0 |
onix_3.0::oapen | OAPEN ONIX 3.0 |
onix_3.0::jstor | JSTOR ONIX 3.0 |
onix_3.0::google_books | Google Books ONIX 3.0 |
onix_3.0::overdrive | OverDrive ONIX 3.0 |
onix_2.1::ebsco_host | EBSCO Host ONIX 2.1 |
csv::thoth | Thoth CSV |
json::thoth | Thoth JSON |
kbart::oclc | OCLC KBART |
bibtex::thoth | Thoth BibTeX |
doideposit::crossref | CrossRef DOI deposit |
onix_2.1::proquest_ebrary | ProQuest Ebrary ONIX 2.1 |
marc21record::thoth | Thoth MARC 21 Record |
marc21markup::thoth | Thoth MARC 21 Markup |
marc21xml::thoth | Thoth MARC 21 XML |