Release Date: 2024-03-11

Histology of Pulmonary Circulation & Related Structures

Seda Keskin (Author)

Release Date: 2024-03-11

The pulmonary circulation is a critical component of the cardiovascular system and facilitates gas exchange between the heart and lungs. The lungs and heart are the main organs in the pulmonary circulation. In addition, the organs of the respiratory system are also involved in the circulating oxygen and carbon dioxide cycle. The process begins with [...]

Media Type
  • PDF

Buy from

Price may vary by retailers

Work TypeBook Chapter
Published inPulmonary Circulation Related Structures
First Page47
Last Page106
DOIhttps://doi.org/10.69860/nobel.9786053358886.2
ISBN978-605-335-888-6 (PDF)
LanguageENG
Page Count60
Copyright HolderNobel Tıp Kitabevleri
Licensehttps://nobelpub.com/publish-with-us/copyright-and-licensing
The pulmonary circulation is a critical component of the cardiovascular system and facilitates gas exchange between the heart and lungs. The lungs and heart are the main organs in the pulmonary circulation. In addition, the organs of the respiratory system are also involved in the circulating oxygen and carbon dioxide cycle. The process begins with the right ventricle pumping oxygen-poor blood into the pulmonary trunk, which bifurcates into the right and left pulmonary arteries. These arteries enter the lungs, where they divide into smaller arterioles and capillaries within the pulmonary alveoli, the primary site for gas exchange. After the gas exchange, pulmonary venules, which merge into larger vessels and eventually form pulmonary veins collected oxygen-rich blood. These vessels complete the pulmonary circuit by carrying oxygen-rich blood to the left atrium of the heart. Pulmonary arteries and veins show different histological features. The bronchi and bronchioles, which conduct the airways within the lungs, also play a supporting role in the pulmonary circulation. The bronchi are lined with pseudostratified ciliated columnar epithelium interspersed with goblet cells that secrete mucus to trap inhaled particles. The underlying lamina propria contains elastic fibres, smooth muscle and seromucous glands that facilitate airway potency and clearance. In conclusion, the pulmonary circulation is a finely tuned system that includes the right ventricle, pulmonary arteries, alveoli, capillaries and pulmonary veins. Each component exhibits specific histological features that support its function in gas exchange and blood oxygenation, which are crucial for maintaining respiratory and cardiovascular health.

Seda Keskin (Author)
Research Assistant, Van Yuzuncu Yil University
https://orcid.org/0000-0002-4726-982X
3Seda Keskin (PhD (c)), completed her undergraduate education at Ondokuz Mayıs University, Ordu Faculty of Arts and Sciences, Department of Biology in 2008. In 2010, she received her first master’s degree in Sakarya University Institute of Science and Technology, Department of Biology, and then completed her second master’s degree in Van Yuzuncu Yil University, Institute of Health Sciences, Department of Medical Histology and Embryology in 2018. She has been continuing her doctorate education at the same university since 2018. She is currently working as a research assistant at Van Yuzuncu Yil University Faculty of Medicine, Department of Basic Medical Sciences, Department of Medical Histology and Embryology. Her research interests include psoriasis, inflammatory skin diseases, mesenchymal stem cells, microbiota, intermittent fasting, aging, UV radiation, electromagnetic field, diabetes, metabolic diseases, cellular therapy, ovarian toxicity and stereology. Keskin has been involved in many national and international scientific articles, book chapters and projects and has presented at various congresses. Her research interests focus on psoriasis, inflammatory skin diseases, inflammasomes and metabolic syndrome.

  • Amann, M. (2012). Pulmonary system limitations to endurance exercise performance in humans. Experimental physiology, 97(3), 311-318.

  • Arackal, A., & Alsayouri, K. (2019). Histology, heart.

  • Arbex, M. A., Santos, U. d. P., Martins, L. C., Saldiva, P. H. N., Pereira, L. A. A., & Braga, A. L. F. (2012). Air pollution and the respiratory system. Jornal brasileiro de pneumologia, 38, 643-655.

  • 4. Bancroft, J. D., & Gamble, M. (2008). Theory and practice of histological techniques. Elsevier health sciences.

  • Buja, L. M., & Butany, J. (Eds.). (2022). Cardiovascular pathology. Academic Press.

  • Carvalho, O., & Gonçalves, C. (2011). Comparative physiology of the respiratory system in the animal kingdom. The open biology journal, 4(1)

  • Clarkson, A. (2013). A text-book of histology: descriptive and practical. For the Use of Students. Butterworth-Heinemann.

  • Cornil, V., & Banvier, L. (2023). A Manual of pathological histology. BoD–Books on Demand.

  • Eurell, J. A. (2004). Histology (Vol. 2). Teton NewMedia.

  • Gartner, L. P. (2020). Textbook of Histology E-Book: Textbook of Histology E-Book. Elsevier Health Sciences.

  • Gunasegaran, J. P. (2016). Textbook of Histology and A Practical guide-E-Book. Elsevier Health Sciences.

  • . Han, M. K., McLaughlin, V. V., Criner, G. J., & Martinez, F. J. (2007). Pulmonary diseases and the heart. Circulation, 116(25), 2992-3005.

  • Heinbockel, T., & Shields, V. D. C. (2019). Histology. BoD–Books on Demand.

  • Hilaire, G., & Duron, B. (1999). Maturation of the mammalian respiratory system. Physiological reviews, 79(2), 325-360.

  • Ionescu, C. M. (2013). The human respiratory system: an analysis of the interplay between anatomy, structure, breathing and fractal dynamics. Springer Science & Business Media.

  • Kerr, J. B. (2010). Functional histology. Mosby International.

  • Kierszenbaum, A. L., & Tres, L. (2015). Histology and Cell Biology: an introduction to pathology E-Book. Elsevier Health Sciences.

  • Lalley, P. M. (2013). The aging respiratory system—pulmonary structure, function and neural control. Respiratory physiology & neurobiology, 187(3), 199-210.

  • Lindberg, M. R. (2017). Diagnostic Pathology: Normal Histology: Diagnostic Pathology: Normal Histology-E-Book. Elsevier Health Sciences.

  • Lopez, A., & Martinson, S. A. (2017). Respiratory system, mediastinum, and pleurae. Pathologic basis of veterinary disease, 471.

  • Lowe, J. S., Anderson, P. G., & Anderson, S. I. (2018). Stevens & Lowe’s Human Histology-Inkling Enhanced E-Book: Stevens & Lowe’s Human Histology-E-Book. Elsevier Health Sciences.

  • Maynard, R. L., & Downes, N. (2019). Anatomy and histology of the laboratory rat in toxicology and biomedical research. Academic Press.

  • O’Dowd, G., Bell, S., & Wright, S. (2023). Wheater’s Functional Histology, E-Book: A Text and Colour Atlas. Elsevier Health Sciences

  • Ovalle, W. K., & Nahirney, P. C. (2020). Netter’s Histology Flash Cards: A Companion to Netter’s Essential Histology. Elsevier Health Sciences.

  • Pawlina, W., & Ross, M. H. (2018). Histology: a text and atlas: with correlated cell and molecular biology. Lippincott Williams & Wilkins.

  • Patwa, A., & Shah, A. (2015). Anatomy and physiology of respiratory system relevant to anaesthesia. Indian journal of anaesthesia, 59(9), 533-541.

  • Rehfeld, A., Nylander, M., & Karnov, K. (2017). Compendium of histology: a theoretical and practical guide.

  • Rindfleisch, E. (2023). A Manual of Pathological Histology: Vol. I. BoD–Books on Demand.

  • Ross, M. H., & Pawlina, W. (2006). Histology. Lippincott Williams & Wilkins.

  • Santacroce, L., Charitos, I. A., Ballini, A., Inchingolo, F., Luperto, P., De Nitto, E., & Topi, S. (2020). The human respiratory system and its microbiome at a glimpse. Biology, 9(10), 318.

  • Sharma, G., & Goodwin, J. (2006). Effect of aging on respiratory system physiology and immunology. Clinical interventions in aging, 1(3), 253-260.

  • Sorensen, V., Jorsal, S. E., & Mousing, J. (2006). Diseases of the respiratory system. Diseases of swine, 9, 149-177.

  • Stocker, J. T. (2001). The respiratory tract. Pediatric pathology, 1, 466-473.

  • Suvarna, K. S., Layton, C., & Bancroft, J. D. (2018). Bancroft’s theory and practice of histological techniques E-Book. Elsevier health sciences.

  • Tawara, S. (2000). Conduction System Of The Mammalian Heart, The: An Anatomico-histological Study Of The Atrioventricular Bundle And The Purkinje Fibers. World Scientific.

  • Taylor, C. R., & Weibel, E. R. (1981). Design of the mammalian respiratory system. I. Problem and strategy. Respiration physiology, 44(1), 1-10.

  • Taylor, A. M., & Bordoni, B. (2020). Histology, blood vascular system.

  • Vasudeva, N., & Mishra, S. (2016). Inderbir Singh’s Textbook of Human Histology: With Color Atlas and Practical Guide. JP Medical Ltd.

  • Yıldızhan, E., & Ulger, B. V. (2022). Histology And Anatomy of the Heart. Reviews in Medical and Health Science, 109.

  • Young, B., O’Dowd, G., & Woodford, P. (2013). Wheater’s Functional Histology E-Book: Wheater’s Functional Histology E-Book. Elsevier Health Sciences

  • Widdicombe, J. G. (1982). Pulmonary and respiratory tract receptors. Journal of Experimental Biology, 100(1), 41-57.

  • Zeleznik, J. (2003). Normative aging of the respiratory system. Clinics in geriatric medicine, 19(1), 1-18.

  • Zepp, J. A., & Morrisey, E. E. (2019). Cellular crosstalk in the development and regeneration of the respiratory system. Nature reviews Molecular cell biology, 20(9), 551-566.

Share This Chapter!