Release Date: 2024-06-10

Imaging in Pediatric Thoracic and Abdominopelvic Tumors

Mehmet Ozturk (Author), Nurullah Dag (Author)

Release Date: 2024-06-10

This section consists of three main titles: Thoracic, Hepatobiliary, and Urogenital Malignancies. In each section, the most common malignancies are discussed under subheadings. The spectrum of pediatric lesions differs from that of adults. Age is also an important criterion for the diagnosis of lesions in children. It should also be noted that lesions associated with [...]

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    Work TypeBook Chapter
    Published inThe Radiology of Cancer
    First Page341
    Last Page364
    DOIhttps://doi.org/10.69860/nobel.9786053359364.25
    Page Count24
    Copyright HolderNobel Tıp Kitabevleri
    Licensehttps://nobelpub.com/publish-with-us/copyright-and-licensing
    This section consists of three main titles: Thoracic, Hepatobiliary, and Urogenital Malignancies. In each section, the most common malignancies are discussed under subheadings. The spectrum of pediatric lesions differs from that of adults. Age is also an important criterion for the diagnosis of lesions in children. It should also be noted that lesions associated with genetic diseases or infections, as well as proliferative and hamartomatous non-neoplastic lesions, are common in this period. Imaging modalities provide useful information for tumor characterization, staging, and treatment planning. Common malignant tumors in each section have been reviewed with radiologic case examples.

    Mehmet Ozturk (Author)
    Professor, Selcuk University
    https://orcid.org/0000-0001-5585-1476
    3Prof. Dr. Mehmet ÖZTÜRK works at Selçuk University Faculty of Medicine, Division of Pediatric Radiology. He completed his medical school education at Erciyes University in 2005. He became a radiologist in 2011 and a pediatric radiologist in 2015. Prof. Dr. ÖZTÜRK founded the division of Pediatric Radiology within Selçuk University Faculty of Medicine in 2019 and currently serves as the head of the division. He is a member of many domestic and international associations related to radiology and pediatric radiology and serves on the board of directors of the pediatric radiology association. Prof. Dr. Mehmet ÖZTÜRK has built a distinguished career in the field of pediatric radiology and has made significant contributions to his field with his studies for more than ten years. As a result of his studies, more than 100 research articles and more than 200 oral and poster presentations have been published. Assoc. Prof. Dr. Nurullah DAĞ graduated from Elazığ Science High School in 2007. He completed his medical education at Gaziantep University in 2014 and his radiology education at Gazi University in 2020. He worked at Malatya Training and Research Hospital until 2024. He received the title of associate professor in 2023. He has been working at İnönü University Faculty of Medicine, Department of Radiology since February 2024. Abdominal and Interventional Radiology are his main fields of interest.

    Nurullah Dag (Author)
    Associate Professor, Inonu University
    https://orcid.org/0000-0002-9342-0244
    3Assoc. Prof. Dr. Nurullah DAĞ graduated from Elazığ Science High School in 2007. He completed his medical education at Gaziantep University in 2014 and his radiology education at Gazi University in 2020. He worked at Malatya Training and Research Hospital until 2024. He received the title of associate professor in 2023. He has been working at İnönü University Faculty of Medicine, Department of Radiology since February 2024. Abdominal and Interventional Radiology are his main fields of interest.Prof. Dr. Mehmet ÖZTÜRK works at Selçuk University Faculty of Medicine, Division of Pediatric Radiology. He completed his medical school education at Erciyes University in 2005. He became a radiologist in 2011 and a pediatric radiologist in 2015. Prof. Dr. ÖZTÜRK founded the division of Pediatric Radiology within Selçuk University Faculty of Medicine in 2019 and currently serves as the head of the division. He is a member of many domestic and international associations related to radiology and pediatric radiology and serves on the board of directors of the pediatric radiology association. Prof. Dr. Mehmet ÖZTÜRK has built a distinguished career in the field of pediatric radiology and has made significant contributions to his field with his studies for more than ten years. As a result of his studies, more than 100 research articles and more than 200 oral and poster presentations have been published.

    • Newman B. Thoracic neoplasms in children. Radiologic Clinics. 2011;49(4):633-64.

    • Orman G, Masand P, Hicks J, Huisman TA, Guillerman RP. Pediatric thoracic mass lesions: beyond the common. European Journal of Radiology Open. 2020;7:100240.

    • Lee EY. Pediatric thoracic oncology disorders. Imaging in pediatric pulmonology. 2020:293-323.

    • Zapala MA, Ho-Fung VM, Lee EY. Thoracic neoplasms in children: contemporary perspectives and imaging assessment. Radiologic Clinics. 2017;55(4):657-76.

    • Dishop MK, Kuruvilla S. Primary and metastatic lung tumors in the pediatric population: a review and 25-year experience at a large children’s hospital. Archives of pathology & laboratory medicine. 2008;132(7):1079-103.

    • Mong A, Epelman M, Darge K. Ultrasound of the pediatric chest. Pediatric radiology. 2012;42:1287-97.

    • Ben-Ami TE, O’Donovan JC, Yousefzadeh DK. Sonography of the chest in children. Radiologic Clinics of North America. 1993;31(3):517-31.

    • Macias CG, Chumpitazi CE. Sedation and anesthesia for CT: emerging issues for providing high-quality care. Pediatric radiology. 2011;41:517-22.

    • Sodhi KS, Krishna S, Saxena AK, Sinha A, Khandelwal N, Lee EY. Clinical application of ‘Justification’and ‘Optimization’principle of ALARA in pediatric CT imaging:“How many children can be protected from unnecessary radiation?”. European journal of radiology. 2015;84(9):1752-7.

    • Ciet P, Tiddens HA, Wielopolski PA, Wild JM, Lee EY, Morana G, et al. Magnetic resonance imaging in children: common problems and possible solutions for lung and airways imaging. Pediatric radiology. 2015;45:1901-15.

    • Gorkem SB, Coskun A, Yikilmaz A, Zurakowski D, Mulkern RV, Lee EY. Evaluation of pediatric thoracic disorders: comparison of unenhanced fast-imaging-sequence 1.5-T MRI and contrast-enhanced MDCT. American Journal of Roentgenology. 2013;200(6):1352-7.

    • Ackman JB. MR imaging of mediastinal masses. Magnetic Resonance Imaging Clinics. 2015;23(2):14164.

    • Uslu L, Donig J, Link M, Rosenberg J, Quon A, Daldrup-Link HE. Value of 18F-FDG PET and PET/CT for evaluation of pediatric malignancies. Journal of Nuclear Medicine. 2015;56(2):274-86.

    • Purz S, Sabri O, Viehweger A, Barthel H, Kluge R, Sorge I, et al. Potential pediatric applications of PET/ MR. Journal of Nuclear Medicine. 2014;55(Supplement 2):32S-9S.

    • Ranganath SH, Lee EY, Restrepo R, Eisenberg RL. Mediastinal masses in children. American Journal of Roentgenology. 2012;198(3):W197-W216.

    • Merten DF. Diagnostic imaging of mediastinal masses in children. AJR American journal of roentgenology. 1992;158(4):825-32.

    • Gun F, Erginel B, Ünüvar A, Kebudi R, Salman T, Celik A. Mediastinal masses in children: experience with 120 cases. Pediatric hematology and oncology. 2012;29(2):141-7.

    • Biko DM, Lichtenberger III JP, Rapp JB, Khwaja A, Huppmann AR, Chung EM. Mediastinal masses in children: radiologic-pathologic correlation. RadioGraphics. 2021;41(4):1186-207.

    • Oschlies I, Burkhardt B, Salaverria I, Rosenwald A, d’Amore ES, Szczepanowski M, et al. Clinical, pathological and genetic features of primary mediastinal large B-cell lymphomas and mediastinal gray zone lymphomas in children. Haematologica. 2011;96(2):262.

    • Mallick S, Jain S, Ramteke P. Pediatric mediastinal lymphoma. Mediastinum. 2020;4.

    • Newman EA, Abdessalam S, Aldrink JH, Austin M, Heaton TE, Bruny J, et al. Update on neuroblastoma. Journal of pediatric surgery. 2019;54(3):383-9.

    • Ahmed AA, Zhang L, Reddivalla N, Hetherington M. Neuroblastoma in children: Update on clinicopathologic and genetic prognostic factors. Pediatric hematology and oncology. 2017;34(3):165-85.

    • Hiorns M, Owens C. Radiology of neuroblastoma in children. European radiology. 2001;11:2071-81.

    • Albany C, Einhorn LH. Extragonadal germ cell tumors: clinical presentation and management. Current opinion in oncology. 2013;25(3):261-5.

    • Ueno T, Tanaka YO, Nagata M, Tsunoda H, Anno I, Ishikawa S, et al. Spectrum of germ cell tumors: from head to toe. Radiographics. 2004;24(2):387-404.

    • Amini B, Huang SY, Tsai J, Benveniste MF, Robledo HH, Lee EY. Primary lung and large airway neoplasms in children: current imaging evaluation with multidetector computed tomography. Radiologic Clinics. 2013;51(4):637-57.

    • Leung SS, Donuru A, Kandula V, Parekh MR, Saul D, editors. Multimodality imaging of pleuropulmonary blastoma: pearls, pitfalls, and differential diagnosis. Seminars in Ultrasound, CT and MRI; 2022: Elsevier.

    • Dupin N, Jary A, Boussouar S, Syrykh C, Gandjbakhche A, Bergeret S, et al. Current and future tools for diagnosis of Kaposi’s sarcoma. Cancers. 2021;13(23):5927.

    • Shah AA, D’Amico TA. Primary chest wall tumors. Journal of the American College of surgeons. 2010;210(3):360-6.

    • La Quaglia MP, editor Chest wall tumors in childhood and adolescence. Seminars in pediatric surgery; 2008: Elsevier.

    • Nam SJ, Kim S, Lim BJ, Yoon C-S, Kim TH, Suh J-S, et al. Imaging of primary chest wall tumors with radiologic-pathologic correlation. Radiographics. 2011;31(3):749-70.

    • Carter BW, Benveniste MF, Betancourt SL, De Groot PM, Lichtenberger III JP, Amini B, et al. Imaging evaluation of malignant chest wall neoplasms. Radiographics. 2016;36(5):1285-306.

    • Das C, Dhingra S, Gupta A, Iyer V, Agarwala S. Imaging of paediatric liver tumours with pathological correlation. Clinical radiology. 2009;64(10):1015-25.

    • Yikilmaz A, George M, Lee EY. Pediatric hepatobiliary neoplasms: an overview and update. Radiologic Clinics. 2017;55(4):741-66.

    • Fernandez-Pineda I, Sandoval JA, Davidoff AM. Hepatic metastatic disease in pediatric and adolescent solid tumors. World journal of hepatology. 2015;7(14):1807.

    • Aronson DC, Meyers RL, editors. Malignant tumors of the liver in children. Seminars in pediatric surgery; 2016: Elsevier.

    • Faingold R, Albuquerque PA, Carpineta L. Hepatobiliary tumors. Radiologic Clinics. 2011;49(4):679-87.

    • Vasireddi AK, Leo ME, Squires JH. Magnetic resonance imaging of pediatric liver tumors. Pediatric Radiology. 2022;52(2):177-88.

    • Schooler GR, Squires JH, Alazraki A, Chavhan GB, Chernyak V, Davis JT, et al. Pediatric hepatoblastoma, hepatocellular carcinoma, and other hepatic neoplasms: consensus imaging recommendations from American College of Radiology Pediatric Liver Reporting and Data System (LI-RADS) Working Group. Radiology. 2020;296(3):493-7.

    • Spector LG, Birch J. The epidemiology of hepatoblastoma. Pediatric blood & cancer. 2012;59(5):776-9.

    • Hager J, Sergi CM. Hepatoblastoma. Exon Publications. 2021:145-64.

    • Miyazaki O, Oguma E, Nishikawa M, Tanami Y, Hosokawa T, Kitami M, et al. Usefulness of central radiologic review in clinical trials of children with hepatoblastoma. Pediatric Radiology. 2023;53(3):367-77.

    • Kelly D, Sharif K, Brown RM, Morland B. Hepatocellular carcinoma in children. Clinics in liver disease. 2015;19(2):433-47.

    • Wang J, Mao Y, Liu Y, Chen Z, Chen M, Lao X, et al. Hepatocellular carcinoma in children and adolescents: clinical characteristics and treatment. Journal of Gastrointestinal Surgery. 2017;21(7):1128-35.

    • Chung EM, Lattin Jr GE, Cube R, Lewis RB, Marichal-Hernández C, Shawhan R, et al. From the archives of the AFIP: pediatric liver masses: radiologic-pathologic correlation part 2. Malignant tumors. Radiographics. 2011;31(2):483-507.

    • Arias GA, Siddiqui I, Navarro OM, Shaikh F, Sayed BA, Chavhan GB. Imaging and clinical features of pediatric hepatocellular carcinoma. Pediatric Radiology. 2021;51:1339-47.

    • Cha DI, Yoo S-Y, Kim JH, Jeon TY, Eo H. Clinical and imaging features of focal nodular hyperplasia in children. American Journal of Roentgenology. 2014;202(5):960-5.

    • Stocker JT, Ishak KG. Undifferentiated (embryonal) sarcoma of the liver. Report of 31 cases. Cancer. 1978;42(1):336-48.

    • Martins-Filho SN, Putra J. Hepatic mesenchymal hamartoma and undifferentiated embryonal sarcoma of the liver: a pathologic review. Hepatic Oncology. 2020;7(2):HEP19.

    • Gabor F, Franchi-Abella S, Merli L, Adamsbaum C, Pariente D. Imaging features of undifferentiated embryonal sarcoma of the liver: a series of 15 children. Pediatric radiology. 2016;46:1694-704.

    • Kebudi R, Görgun Ö, Ayan İ, CoŞar R, Bilgiç B. Rhabdomyosarcoma of the biliary tree. Pediatrics international. 2003;45(4):469-71.

    • Mathew D, de Lima H, Mahomed N. Embryonal rhabdomyosarcoma of the biliary tree in a paediatric patient–A rare cause of obstructive jaundice. SA Journal of Radiology. 2019;23(1).

    • Liu T, Zhao T, Shi C, Chen L. Pancreatoblastoma in children: Clinical management and literature review. Translational oncology. 2022;18:101359.

    • Glick RD, Pashankar FD, Pappo A, LaQuaglia MP. Management of pancreatoblastoma in children and young adults. Journal of Pediatric Hematology/Oncology. 2012;34:S47-S50.

    • Chung EM, Travis MD, Conran RM. Pancreatic tumors in children: radiologic-pathologic correlation. Radiographics. 2006;26(4):1211-38.

    • Frantz VK. Tumors of the pancreas: Armed Forces Institute of Pathology; 1959.

    • Ahmed TS, Chavhan GB, Navarro OM, Traubici J. Imaging features of pancreatic tumors in children: 13-year experience at a pediatric tertiary hospital. Pediatric radiology. 2013;43:1435-43.

    • Ladino-Torres MF, Strouse PJ. Gastrointestinal tumors in children. Radiologic Clinics. 2011;49(4):66577.

    • Pappo AS, Janeway KA. Pediatric gastrointestinal stromal tumors. Hematology/oncology clinics of North America. 2009;23(1):15-34.

    • George M, Perez-Rosello JM, Yikilmaz A, Lee EY. Pediatric urinary system neoplasms: an overview and update. Radiologic Clinics. 2017;55(4):767-84.

    • Stanescu AL, Acharya PT, Lee EY, Phillips GS. Pediatric Renal Neoplasms:: MR Imaging–Based Practical Diagnostic Approach. Magnetic Resonance Imaging Clinics. 2019;27(2):279-90.

    • Balassy C, Navarro OM, Daneman A. Adrenal masses in children. Radiologic Clinics. 2011;49(4):711-27.

    • Lowe LH, Isuani BH, Heller RM, Stein SM, Johnson JE, Navarro OM, et al. Pediatric renal masses: Wilms tumor and beyond. Radiographics. 2000;20(6):1585-603.

    • Picarsic J, Reyes-Múgica M. Phenotype and immunophenotype of the most common pediatric tumors. Applied immunohistochemistry & molecular morphology. 2015;23(5):313-26.

    • Davidoff AM. Wilms tumor. Advances in pediatrics. 2012;59(1):247-67.

    • Friedman AD. Wilms tumor. Pediatrics in Review. 2013;34(7):328-30.

    • Szychot E, Apps J, Pritchard-Jones K. Wilms’ tumor: biology, diagnosis and treatment. Translational pediatrics. 2014;3(1):12.

    • Servaes SE, Hoffer FA, Smith EA, Khanna G. Imaging of Wilms tumor: an update. Pediatric radiology. 2019;49:1441-52.

    • Beckwith JB, Kiviat NB, Bonadio JF. Nephrogenic rests, nephroblastomatosis, and the pathogenesis of Wilms’ tumor. Pediatric pathology. 1990;10(1-2):1-36.

    • Geller E, Kochan PS. Renal neoplasms of childhood. Radiologic Clinics. 2011;49(4):689-709.

    • McHugh K. Renal and adrenal tumours in children. Cancer imaging. 2007;7(1):41.

    • Sebire NJ, Vujanic GM. Paediatric renal tumours: recent developments, new entities and pathological features. Histopathology. 2009;54(5):516-28.

    • Spreafico F, Collini P, Terenziani M, Marchianò A, Piva L. Renal cell carcinoma in children and adolescents. Expert Review of Anticancer Therapy. 2010;10(12):1967-78.

    • Indolfi P, Terenziani M, Casale F, Carli M, Bisogno G, Schiavetti A, et al. Renal cell carcinoma in children: a clinicopathologic study. Journal of clinical oncology. 2003;21(3):530-5.

    • Bruder E, Passera O, Harms D, Leuschner I, Ladanyi M, Argani P, et al. Morphologic and molecular characterization of renal cell carcinoma in children and young adults. The American journal of surgical pathology. 2004;28(9):1117-32.

    • Lin X, Wu D, Chen C, Zheng N. Clinical characteristics of adrenal tumors in children: a retrospective review of a 15-year single-center experience. International urology and nephrology. 2017;49:381-5.

    • Zhang K, Zhang Y, Zhang Y, Chao M. A retrospective analysis of the clinical characteristics of 207 hospitalized children with adrenal masses. Frontiers in Pediatrics. 2023;11.

    • Lockhart ME, Smith JK, Kenney PJ. Imaging of adrenal masses. European journal of radiology. 2002;41(2):95-112.

    • Siegel MJ. Pelvic tumors in childhood. Radiologic Clinics of North America. 1997;35(6):1455-75.

    • Shah RU, Lawrence C, Fickenscher KA, Shao L, Lowe LH. Imaging of pediatric pelvic neoplasms. Radiologic Clinics. 2011;49(4):729-48.

    • Erol Ob, Yekeler E. Pediatrik Onkolojik Görüntüleme. Turkiye Klinikleri Radiology-Special Topics. 2013;6(1):33-42.

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