Release Date: 2024-06-10

Pharmacological and Phytochemical Contents of Thymbra Taxa

Mizgin Ermanoglu (Author), Mustafa Oksuz (Author), Beyza Nur Yilmaz (Author), Turgut Taskin (Author)

Release Date: 2024-06-10

Thymbra, known as Mediterranean thyme, is a genus of plants in the Lamiaceae family. Thymbra calostachya (Rech.f.) Rech.f., Thymbra capitata (L.) Cav., Thymbra sintenisii Bornm. &Azn., Thymbra spicata L. and Thymbra spicata subsp. intricata (P.H. Davis) R. Morales are species belonging to the genus Thymbra. The Eastern Mediterranean region is considered to be the genus’s [...]

Media Type
    Buy from

    Price may vary by retailers

    Work TypeBook Chapter
    Published inMedicinal Spices
    First Page227
    Last Page238
    DOIhttps://doi.org/10.69860/nobel.9786053359340.14
    Page Count12
    Copyright HolderNobel Tıp Kitabevleri
    Licensehttps://nobelpub.com/publish-with-us/copyright-and-licensing

    Thymbra, known as Mediterranean thyme, is a genus of plants in the Lamiaceae family. Thymbra calostachya (Rech.f.) Rech.f., Thymbra capitata (L.) Cav., Thymbra sintenisii Bornm. &Azn., Thymbra spicata L. and Thymbra spicata subsp. intricata (P.H. Davis) R. Morales are species belonging to the genus Thymbra. The Eastern Mediterranean region is considered to be the genus’s gene center. The Thymbra genus comprises three species and five taxa in the Turkish flora, of which two are endemic. Many people use the dried or fresh leaves and flowers of Thymbra species as a spice in salads and other dishes, as well as in hot beverages. Folk medicine uses the plant’s aerial parts to treat rheumatism, colic, bronchitis, asthma, cough, and diarrhea The pharmaceutical industry uses Thymbra species as raw materials because of their significant pharmacological properties and phytochemical components, which have been found in numerous nations.

    Mizgin Ermanoglu (Author)
    Pharmacist, Marmara University
    https://orcid.org/0000-0003-3146-1988
    3Mizgin Ermanoğlu completed his undergraduate education at Marmara University Faculty of Pharmacy in 2021. She graduated from the Pharmacognosy thesis master’s program of the same university in 2024. As of 2021, he works as a public pharmacist in Mardin and continues his scientific activities at the same time. Her areas of expertise are medicinal plants, active compounds ısolation from medinical plants, Biological activity, HPLC-DAD and delivery systems for herbal medicines

    Mustafa Oksuz (Author)
    Marmara University
    https://orcid.org/0000-0003-2743-8582
    3I graduated from Marmara Universıty Faculty of Pharmacy In 2022. I am doing a Master’s Degree in the Department of Medical Bıochemıstry at Mersın Universıty as of 2023. My main field of work is medicinal plants, phytochemical components, liposomal and niosomal carrier systems loaded with phytochemicals. I also have studies on non viral gene therapy.

    Beyza Nur Yilmaz (Author)
    Res. Assist, Marmara University
    https://orcid.org/0000-0002-4418-3182
    3Beyza Nur Yılmaz completed her master’s degree in the Department of Pharmacognosy at Marmara University, Faculty of Pharmacy in 2023. She started her doctorate in the same department in the same year. She was appointed as a research assistant to this department in 2023. She completed her master’s thesis on bioactivity, formulation and hplc analysis of medicinal plants and continues her studies in these areas.

    Turgut Taskin (Author)
    Associate Professor, Marmara University
    https://orcid.org/0000-0001-8475-6478
    3Turgut Taşkın completed his doctorate in 2016 at Marmara University, Faculty of Pharmacy, Department of Pharmacognosy. He was appointed as an assistant professor in this department in 2017.He has been working as an Associate Professor since 2021. His areas of expertise are medicinal plants, active compounds ısolation from medinical plants, Biological activity, HPLC-DAD and delivery systems for herbal medicines

    • Akkol, E. K., Avcı, G., Küçükkurt, I., Keleş, H., Tamer, U., Ince, S., & Yesilada, E. (2009). Cholesterol-reducer, antioxidant and liver protective effects of Thymbra spicata L. var. spicata. Journal of ethnopharmacology, 126(2), 314-319.

    • Askun, T., Tumen, G., Satil, F., & Ates, M. (2009). In vitro activity of methanol extracts of plants used as spices against Mycobacterium tuberculosis and other bacteria. Food chemistry, 116(1), 289-294

    • Avci, G., Kupeli, E., Eryavuz, A., Yesilada, E., & Kucukkurt, I. (2006). Antihypercholesterolaemic and antioxidant activity assessment of some plants used as remedy in Turkish folk medicine. Journal of ethnopharmacology, 107(3), 418-423

    • Babaç, M.T. (2004). Possibility of an information system on plants of South-West Asia with particular reference to the Turkish plants data service (TUBIVES). Turk J Botany, 28(1-2), 119-127.

    • Başer, K.H.C., Ermin, N., Özek, T., Demir Çakmak, B., Tümen, G., & Duman, H. (1996). Essential Oils of Thymbra sintenisii Bornm. et Aznav. subsp. isaurica P.H. Davis and Origanum leptocladum Boiss. J Essent Oil Res, 8(6), 675-76.

    • Baydar, H., Sağdiç, O., Özkan, G., & Karadoğan, T. (2004). Antibacterial activity and composition of essential oils from Origanum, Thymbra and Satureja species with commercial importance in Turkey. Food control, 15(3), 169-172.

    • Baytok, E., Kara, K., Aksu, T., Guclu, B., Özkaya, S., Denek, N., & Akçay, A. (2017). The effect of Mediterranean thyme (Thymbra spicata L. var. spicata) essential oil on fattening performance and ruminal parameters in lamb. Journal of Animal and Feed Sciences, 26(4), 319-325.

    • Bounatirou, S., Smiti, S., Miguel, M.G., Faleiro, L., Rejeb, M.N., Neffati, M., Costa, M.M., Figueiredo, A.C., Barroso, J.G.,&Pedro LG. (2007). Chemical composition, antioxidant and antibacterial activities of the essential oils isolated from Tunisian Thymus capitatus Hoff et Link. Food Chem J, 105(1), 146-155.

    • Davis, P.H. (ed.) (1982). Flora of Turkey and the Aegean Islands, volüme 7. Edinburgh University Press.

    • Dirican, E., Turkez, H., & Toğar, B. (2012). Modulatory effects of Thymbra spicata L. different extracts against the mercury induced genotoxicity in human lymphocytes in vitro. Cytotechnology, 64, 181-186.

    • Doğan, S., Turan, P., Doğan, M., Arslan, O., & Alkan, M. (2007). Timbra bitkisinin (Thymbra spicata L. var. spicata) yapraklarından peroksidazın kısmi karakterizasyonu. Avrupa Gıda Araştırması ve Teknolojisi, 225 , 865-871.

    • Eruygur, N., Çetin, S., Ataş, M., & Çevik, Ö. (2017). Thymbra spicata L. var. spicata etanol ekstresinin antioksidan, antimikrobiyal ve sitotoksik etkisinin araştırılması. Cumhuriyet Medical Journal, 39(3), 531-538.

    • Eruygur, N., Çetin, S., Ataş, M., & Çevik, Ö. A. (2017). study on the antioxidant, antimicrobial and cytotoxic activity of Thymbra spicata L. var. spicata ethanol extract.  Cumhuriyet Medical Journal, 39(3), 531-538

    • Gedik, O., Uslu, Ö.S., & Çınar, O. (2022). Determination of Essential Oil Components and Plant Nutrient Element of Thymbra spicata Species. International Congress on Innovation Technologies & Engineering, Turkey (İzmir).

    • Güner, A., Özhatay, N., Ekim, T., & Başer, K.H.C. (2000). Flora of Turkey and the East Aegean Islands (Supplement 2), Vol. 11. Edinburgh: Edinburgh University Press

    • Gür, T., Karahan, F., Baş, Z., & Türkoğlu, V. (2020). The Determination of Inhibition Effect of Extracts of Thymbra sintenisii Bornm. et Aznav. Subsp on Angiotensin Converting Enzyme. Journal of the Institute of Science and Technology, 10(3), 1848-1856.

    • Hayoglu, I., Basyigit, B., Hayoglu, G., & Atasoy, A. F. (2016). Cream zahter: a functional food some chemical and sensory properties. Current Research in Nutrition and Food Science, 4(1), 32-36.

    • Hayoglu, I., Basyigit, B., Hayoglu, G., & Atasoy, A. F. (2016). Cream zahter: a functional food some chemical and sensory properties. Current Research in Nutrition and Food Science, 4(1), 32-36.

    • Hazzit, M., Baaliouamer, A., Veríssimo, A. R., Faleiro, M. L., & Miguel, M. G. (2009). Chemical composition and biological activities of Algerian Thymus oils. Food chemistry, 116(3), 714-721.

    • Hepokur, C., Misir, S., Çiçek, M., Yaylim, I., & Zeybek, U. (2020a). Evaluation of antioxidant and anticancer effects of Thymbra sintenisii subsp. isaurica extract. Journal of cancer research and therapeutics, 16(4), 822-827.

    • Hepokur, C., Misir, S., Tunç, T., Tutar, U., Hepokur, A. I., & Çiçek, M. (2020b). In vitro antimicrobial, antioxidant, cytotoxic activities, and wound healing potential of Thymbra capitata ethanolic extract. Turkish Journal of Biochemistry, 45(6), 843-849

    • Kaya, D.A., Arslan, M., İnan, M., & Başkaya, S. (2013). Diurnal changes on content and composition of Thymbra spicata L. Essential Oil. Research Journal of Biological Sciences, 8(1), 6-10.

    • Kirkan, B., Sarikurkcu, C., & Amarowicz, R. (2019). Composition, and antioxidant and enzyme‐inhibition activities, of essential oils from Satureja thymbra and Thymbra spicata var. spicata. Flavour and fragrance journal, 34(6), 436-442

    • Kizil, S. (2010). Determination of essential oil variations of Thymbra spicata L. var. spicata naturally growing in the wild flora of East Mediterranean and Southeastern Anatolia regions of Turkey. Ind Crop Prod, 32, 593-600.

    • Kizil, S., Hasimi, N., & Tolan, V. (2014). Biological activities of Origanum, Satureja, Thymbra and Thymus species grown in Turkey. Journal of Essential Oil Bearing Plants, 17(3), 460-468

    • Köten, M., & Satouf, M. (2019). Farklı Formülasyonlarda Kahvaltılık Zahter Üretimi Ve Bazı Kalite Özelliklerinin Belirlenmesi. Gıda, 44(3), 513-522.

    • Maral, H., Türk, M., Çalışkan, T., & Kırıcı, S. (2017). Chemical composition and antioxidant activity of essential oils of six Lamiaceae plants growing in Southern Turkey. Natural Volatiles and Essential Oils, 4(4), 62-68.

    • Marković, T., Chatzopoulou, P., Petrović, J., Nikolić, M., Glamočlija, J., Ćirić, A., & Soković, M. (2011). Chemical analysis and antimicrobial activities of the essential oils of Satureja thymbra L. and Thymbra spicata L. and their main components. Archives of Biological Sciences, 63(2), 457-464.

    • Özcan, M. (2004). Mineral contents ofsome plants used as condimentsin Turkey. Foodchemistry, 84(3), 437-440.

    • Öztürk, M. (2012). Anticholinesterase and antioxidant activities of Savoury (Satureja thymbra L.) with identified major terpenes of the essential oil. Food Chemistry, 134(1), 48-54.

    • Prasanth Reddy, V., Ravi Vital, K., Varsha, P. V., & Satyam, S. (2014). Review on Thymus vulgaris traditional uses and pharmacological properties. Med Aromat Plants, 3(164), 2167-0412.

    • Sadikoğlu, N. (2005). Kekik olarak kullanılan türler üzerinde farmasötik botanik araştırmalar. Istanbul University Faculty of Pharmacy-Doctoral Thesis, 113

    • Sarac, N., Ugur, A., & Duru, M. E. (2009). Antimicrobial activity and chemical composition of the essential oils of Thymbra spicata var. intricata. International Journal of Green Pharmacy (IJGP), 3(1), 24-28.

    • Sarıkaya, A. G. (2019). Leaf and flower volatile oil components of two thyme taxa Origanum onites L. and Thymbra spicata var. spicata L. in Turkey. Avrupa Bilim ve Teknoloji Dergisi, (17), 346-350

    • Tercan, H. S., Ayanoglu, F., & Bahadirli, N. P. (2016). Determination of heavy metal contents and some basic aspects of widely used herbal teas in Turkey. Nature, 3, 4.

    • Tercan, H. S., Ayanoglu, F., & Bahadirli, N. P. (2016). Determination of heavy metal contents and some basic aspects of widely used herbal teas in Turkey. Nature, 3, 4

    • Tümen, G., Başer, K.H.C., Özek, T., Ermin, N., & Duman, H. (1997). The essential oil of Thymbra sintenisii Bornm&Aznav. subsp. sintenisii. J Essent Oil Res, 9, 355-56.

    • Tümen, G., Ermin, N., Özek, T., Kürkçüoğlu, M., & Başer, K.H.C. (1994). Composition of essential oils from two varieties of Thymbra spicata L. J Essent Oil Res, 6, 463-568

    • Uçan, F., Kulak, M., Çimen, G., Şekeroğlu, N. (2014). Kahvaltılık Zahterin Besin Değeri Açısından Değerlendirilmesi, 4. Geleneksel Gıdalar Sempozyumu, Turkey (Adana).

    • Uysal, İ., Muhammed, F.S., Sevindik, M., Şabik, A.E., Sevindik, E., & Doğan, M. (2023). Thymbra cinsi: kullanım alanları, fitokimyasal içerikleri ve biyolojik aktiviteleri üzerine bir inceleme. Mısır Beslenme Dergisi, 1-12.

    onix_3.0::thothThoth ONIX 3.0
    onix_3.0::project_museProject MUSE ONIX 3.0
    onix_3.0::oapenOAPEN ONIX 3.0
    onix_3.0::jstorJSTOR ONIX 3.0
    onix_3.0::google_booksGoogle Books ONIX 3.0
    onix_3.0::overdriveOverDrive ONIX 3.0
    onix_2.1::ebsco_hostEBSCO Host ONIX 2.1
    csv::thothThoth CSV
    json::thothThoth JSON
    kbart::oclcOCLC KBART
    bibtex::thothThoth BibTeX
    doideposit::crossrefCrossRef DOI deposit
    onix_2.1::proquest_ebraryProQuest Ebrary ONIX 2.1
    marc21record::thothThoth MARC 21 Record
    marc21markup::thothThoth MARC 21 Markup
    marc21xml::thothThoth MARC 21 XML

    Share This Chapter!