Hepatic and Splenic Sarcoidosis

Sarcoidosis, a multisystem inflammatory disorder of unknown etiology, often manifests in the liver and spleen, posing unique challenges in clinical management. Hepatic sarcoidosis presents with a spectrum of manifestations, from asymptomatic hepatomegaly to advanced fibrosis and cirrhosis. Splenic involvement, characterized by splenomegaly and occasional hypersplenism, underscores the systemic nature of the disease.
This chapter delves into the epidemiology, pathophysiology, clinical presentations, diagnostic strategies, and therapeutic approaches specific to hepatic and splenic sarcoidosis. Understanding these complexities is crucial for tailored patient care and optimal outcomes in this intricate facet of sarcoidosis.