In summary, neurodegenerative diseases are multifactorial disorders marked by the degeneration and eventual death of nerve cells, leading to structural and functional deterioration. Alzheimer’s, Parkinson’s, Huntington’s, Amyotrophic Lateral Sclerosis, and Multiple Sclerosis are notable examples of such diseases, impacting quality of life and often progressing rapidly. While there is currently no definitive cure for these conditions, treatment strategies focus on enhancing quality of life by slowing disease progression. However, chronic use of existing therapeutic interventions and medications can cause serious side effects. This situation has led patients to turn to alternative medicine practices.A prominent approach among complementary medicine practices is the use of medicinal plants with neuroprotective properties. These plants can aid in brain injury recovery and enhance learning and memory functions through the stimulation of new synapse formation. These plants containing phytochemicals may be effective in the developmental mechanisms of neurodegenerative diseases and may favourably affect the prognosis of the disease. Therefore, phytochemical, pharmacological and clinical research on medicinal plants may make promising contributions to the development of naturally derived drugs for neurodegenerative diseases.