Climate change poses a significant threat to global agriculture, particularly in vulnerable regions like the Küçük Menderes Basin in Türkiye. Research indicates that over the next 70 years, this region, known for its agricultural productivity, is projected to experience temperature increases of 3-5°C and precipitation decreases of 10-20%, severely impacting agricultural yields and quality. To ensure the long-term sustainablity of agriculture in the Küçük Menderes Basin amidst escalating climate change, a comprehensive and proactive strategy that transcends isolated crop adaptations is essential. To achieve this, enhancing regional studies is essential, along with the planning, development, and implementation of action plans and methods required for climate change adaptation and mitigation. Such methods encompass a range of approaches, including, but not limited to, pressurized irrigation systems and the adoption of good and organic agricultural practices. The successful implementation of mitigation and adaptation strategies hinges on a participatory approach, ensuring these strategies are determined in collaboration with all stakeholders.