This chapter reveals the recent increase in the use of Apitherapy as a supportive alternative patient treatment in conjunction with modern medicine. It also explores the reasons for its use and highlights its benefits. In the literature, there are many histologic studies with bee products such as propolis, bee venom, royal jelly and bee bread. Bee products have recently become one of the most widely used food supplements due to their anticarcinogenic, antimicrobial, antiviral and anti-inflammatory effects. Considering the beneficial results of apitherapy on humans, more studies are needed to contribute to the literature in the future.