1. Fosnocht K. M EJ. Approach to the adult patient with fatigue. Wolters Kluwer 2023.
2. Engleberg NC. Chronic Fatigue Syndrome (Systemic Exertion Intolerance Disease). In: Bennett J. E. DR, Blaser M. J. , ed. Mandell, Douglas, And Bennett’s Principles And Practice of Infecti-
ous Diseases. 9th ed. Philadelphia Elsevier; 2020:1787-1794
3. Crowley N, Nelson M, Stovin S. Epidemiological aspects of an outbreak of encephalomyelitis at the Royal Free Hospital, London, in the summer of 1955. J Hyg (Lond) 1957;55(1):102-22. DOI:
10.1017/s0022172400061295.
4. Holmes GP, Kaplan JE, Gantz NM, et al. Chronic fatigue syndrome: a working case definition. Ann Intern Med 1988;108(3):387-9. DOI: 10.7326/0003-4819-108-3-387.
5. Fukuda K, Straus SE, Hickie I, Sharpe MC, Dobbins JG, Komaroff A. The chronic fatigue syndrome: a comprehensive approach to its definition and study. International Chronic Fatigue
Syndrome Study Group. Ann Intern Med 1994;121(12):953-9. DOI: 10.7326/0003-4819-121-12-199412150-00009.
6. Kim E. A brief history of chronic fatigue syndrome. JAMA 1994;272(13):1070-1. DOI: 10.1001/jama.272.13.1070.
7. Steele L, Dobbins JG, Fukuda K, et al. The epidemiology of chronic fatigue in San Francisco. Am J Med 1998;105(3A):83S-90S. DOI: 10.1016/s0002-9343(98)00158-2.
8. Organization WH. Chronic Fatigue Syndrome. 2024.
9. Bates DW, Schmitt W, Buchwald D, et al. Prevalence of fatigue and chronic fatigue syndrome in a primary care practice. Arch Intern Med 1993;153(24):2759-65. (https://www.ncbi.nlm.nih.
gov/pubmed/8257251).
10. Gunn WJ, Connell DB, Randall B. Epidemiology of chronic fatigue syndrome: the Centers for Disease Control Study. Ciba Found Symp 1993;173:83-93; discussion 93-101. DOI:
10.1002/9780470514382.ch6.
11. Estevez-Lopez F, Mudie K, Wang-Steverding X, et al. Systematic Review of the Epidemiological Burden of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Across Europe: Current
Evidence and EUROMENE Research Recommendations for Epidemiology. J Clin Med 2020;9(5). DOI: 10.3390/jcm9051557.
12. Vahratian A, Lin, J.M.S., Bertolli, J., Unger, E.R. Myalgic Encephalomyelitis/Chronic Fatigue Syndrome in Adults: United States, 2021–2022. December 2023 ed: U.S. DEPARTMENT OF
HEALTH AND HUMAN SERVICES, Centers for Disease Control and Prevention, National Center for Health Statistics; 2023.
13. Bakken IJ, Tveito K, Gunnes N, et al. Two age peaks in the incidence of chronic fatigue syndrome/myalgic encephalomyelitis: a population-based registry study from Norway 2008-2012. BMC Med
2014;12:167. DOI: 10.1186/s12916-014-0167-5.
14. Eyigor S, Ozdedeli S, Durmaz B. The prevalence of generalized soft tissue rheumatic conditions in Turkish medical students. J Clin Rheumatol 2008;14(2):65-8. DOI: 10.1097/RHU.
0b013e31816b1920.
15. Terzi R, Altin F. [The prevalence of low back pain in hospital staff and its relationship with chronic fatigue syndrome and occupational factors]. Agri 2015;27(3):149-54. DOI: 10.5505/
agri.2015.26121.
16. Kerr JR, Burke B, Petty R, et al. Seven genomic subtypes of chronic fatigue syndrome/myalgic encephalomyelitis: a detailed analysis of gene networks and clinical phenotypes. J Clin Pathol
2008;61(6):730-9. DOI: 10.1136/jcp.2007.053553.
17. Katz BZ, Shiraishi Y, Mears CJ, Binns HJ, Taylor R. Chronic fatigue syndrome after infectious mononucleosis in adolescents. Pediatrics 2009;124(1):189-93. DOI: 10.1542/peds.2008-1879.
18. Oakes B, Hoagland-Henefield M, Komaroff AL, Erickson JL, Huber BT. Human endogenous retrovirus-K18 superantigen expression and human herpesvirus-6 and human herpesvirus-7 viral
loads in chronic fatigue patients. Clin Infect Dis 2013;56(10):1394-400. DOI: 10.1093/cid/cit086.
19. Davis HE, McCorkell L, Vogel JM, Topol EJ. Long COVID: major findings, mechanisms and recommendations. Nat Rev Microbiol 2023;21(3):133-146. DOI: 10.1038/s41579-022-00846-2.
20. Wildman MJ, Smith EG, Groves J, Beattie JM, Caul EO, Ayres JG. Chronic fatigue following infection by Coxiella burnetii (Q fever): ten-year follow-up of the 1989 UK outbreak cohort. QJM
2002;95(8):527-38. DOI: 10.1093/qjmed/95.8.527.
21. Straus SE, Fritz S, Dale JK, Gould B, Strober W. Lymphocyte phenotype and function in the chronic fatigue syndrome. J Clin Immunol 1993;13(1):30-40. DOI: 10.1007/BF00920633.
22. Caligiuri M, Murray C, Buchwald D, et al. Phenotypic and functional deficiency of natural killer cells in patients with chronic fatigue syndrome. J Immunol 1987;139(10):3306-13. (https://
www.ncbi.nlm.nih.gov/pubmed/2824604).
23. Barker E, Fujimura SF, Fadem MB, Landay AL, Levy JA. Immunologic abnormalities associated with chronic fatigue syndrome. Clin Infect Dis 1994;18 Suppl 1:S136-41. DOI: 10.1093/clini-
ds/18.supplement_1.s136.
24. Bou-Holaigah I, Rowe PC, Kan J, Calkins H. The relationship between neurally mediated hypotension and the chronic fatigue syndrome. JAMA 1995;274(12):961-7. (https://www.ncbi.nlm.
nih.gov/pubmed/7674527).
25. Wyller VB, Godang K, Morkrid L, Saul JP, Thaulow E, Walloe L. Abnormal thermoregulatory responses in adolescents with chronic fatigue syndrome: relation to clinical symptoms. Pediatrics
2007;120(1):e129-37. DOI: 10.1542/peds.2006-2759.
26. Wyller VB, Saul JP, Walloe L, Thaulow E. Sympathetic cardiovascular control during orthostatic stress and isometric exercise in adolescent chronic fatigue syndrome. Eur J Appl Physiol
2008;102(6):623-32. DOI: 10.1007/s00421-007-0634-1.
27. Naschitz JE, Rosner I, Rozenbaum M, et al. The head-up tilt test with haemodynamic instability score in diagnosing chronic fatigue syndrome. QJM 2003;96(2):133-42. DOI: 10.1093/qjmed/
hcg018.
28. Peterson PK, Pheley A, Schroeppel J, et al. A preliminary placebo-controlled crossover trial of fludrocortisone for chronic fatigue syndrome. Arch Intern Med 1998;158(8):908-14. DOI:
10.1001/archinte.158.8.908.
29. Naviaux RK, Naviaux JC, Li K, et al. Metabolic features of chronic fatigue syndrome. Proc Natl Acad Sci U S A 2016;113(37):E5472-80. DOI: 10.1073/pnas.1607571113.
30. Parker AJ, Wessely S, Cleare AJ. The neuroendocrinology of chronic fatigue syndrome and fibromyalgia. Psychol Med 2001;31(8):1331-45. DOI: 10.1017/s0033291701004664.
31. Young AH, Sharpe M, Clements A, Dowling B, Hawton KE, Cowen PJ. Basal activity of the hypothalamic-pituitary-adrenal axis in patients with the chronic fatigue syndrome (neurasthenia).
Biol Psychiatry 1998;43(3):236-7. DOI: 10.1016/S0006-3223(97)00404-6.
32. Buchwald D, Herrell R, Ashton S, et al. A twin study of chronic fatigue. Psychosom Med 2001;63(6):936-43. DOI: 10.1097/00006842-200111000-00012.
33. Byrnes A, Jacks A, Dahlman-Wright K, et al. Gene expression in peripheral blood leukocytes in monozygotic twins discordant for chronic fatigue: no evidence of a biomarker. PLoS One
2009;4(6):e5805. DOI: 10.1371/journal.pone.0005805.
34. Goertzel BN, Pennachin C, de Souza Coelho L, Gurbaxani B, Maloney EM, Jones JF. Combinations of single nucleotide polymorphisms in neuroendocrine effector and receptor genes predict
chronic fatigue syndrome. Pharmacogenomics 2006;7(3):475-83. DOI: 10.2217/14622416.7.3.475.
35. Yelin D, Moschopoulos CD, Margalit I, et al. ESCMID rapid guidelines for assessment and management of long COVID. Clin Microbiol Infect 2022;28(7):955-972. DOI: 10.1016/j.
cmi.2022.02.018.
36. Hartung TJ, Neumann C, Bahmer T, et al. Fatigue and cognitive impairment after COVID-19: A prospective multicentre study. EClinicalMedicine 2022;53:101651. DOI: 10.1016/j.ec-
linm.2022.101651.
37. Tziastoudi M, Cholevas C, Stefanidis I, Theoharides TC. Genetics of COVID-19 and myalgic encephalomyelitis/chronic fatigue syndrome: a systematic review. Ann Clin Transl Neurol
2022;9(11):1838-1857. DOI: 10.1002/acn3.51631.
38. Soriano JB, Murthy S, Marshall JC, Relan P, Diaz JV, Condition WHOCCDWGoP-C-. A clinical case definition of post-COVID-19 condition by a Delphi consensus. Lancet Infect Dis
2022;22(4):e102-e107. DOI: 10.1016/S1473-3099(21)00703-9.
39. Grach SL, Seltzer J, Chon TY, Ganesh R. Diagnosis and Management of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome. Mayo Clin Proc 2023;98(10):1544-1551. DOI: 10.1016/j.
mayocp.2023.07.032.
40. Aaron LA, Burke MM, Buchwald D. Overlapping conditions among patients with chronic fatigue syndrome, fibromyalgia, and temporomandibular disorder. Arch Intern Med 2000;160(2):221-
7. DOI: 10.1001/archinte.160.2.221.
41. Beyond Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Redefining an Illness. Washington (DC)2015.
42. Bateman L, Bested AC, Bonilla HF, et al. Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Essentials of Diagnosis and Management. Mayo Clin Proc 2021;96(11):2861-2878. DOI:
10.1016/j.mayocp.2021.07.004.
43. Roerink ME, Bredie SJH, Heijnen M, Dinarello CA, Knoop H, Van der Meer JWM. Cytokine Inhibition in Patients With Chronic Fatigue Syndrome: A Randomized Trial. Ann Intern Med
2017;166(8):557-564. DOI: 10.7326/M16-2391.
44. Reid SF, Chalder T, Cleare A, Hotopf M, Wessely S. Chronic fatigue syndrome. BMJ Clin Evid 2008;2008 (https://www.ncbi.nlm.nih.gov/pubmed/19445810).
45. Larun L, Brurberg KG, Odgaard-Jensen J, Price JR. Exercise therapy for chronic fatigue syndrome. Cochrane Database Syst Rev 2017;4(4):CD003200. DOI: 10.1002/14651858.CD003200.
pub7.
46. Korszun A, Sackett-Lundeen L, Papadopoulos E, et al. Melatonin levels in women with fibromyalgia and chronic fatigue syndrome. J Rheumatol 1999;26(12):2675-80. (https://www.ncbi.nlm.
nih.gov/pubmed/10606381).
47. Hobday RA, Thomas S, O’Donovan A, Murphy M, Pinching AJ. Dietary intervention in chronic fatigue syndrome. J Hum Nutr Diet 2008;21(2):141-9. DOI: 10.1111/j.1365-277X.2008.00857.x.
48. Price JR, Mitchell E, Tidy E, Hunot V. Cognitive behaviour therapy for chronic fatigue syndrome in adults. Cochrane Database Syst Rev 2008;2008(3):CD001027. DOI: 10.1002/14651858.
CD001027.pub2.
49. Bombardier CH, Buchwald D. Outcome and prognosis of patients with chronic fatigue vs chronic fatigue syndrome. Arch Intern Med 1995;155(19):2105-10. (https://www.ncbi.nlm.nih.gov/
pubmed/7575071).
50. Roberts E, Wessely S, Chalder T, Chang CK, Hotopf M. Mortality of people with chronic fatigue syndrome: a retrospective cohort study in England and Wales from the South London and
Maudsley NHS Foundation Trust Biomedical Research Centre (SLaM BRC) Clinical Record Interactive Search (CRIS) Register. Lancet 2016;387(10028):1638-43. DOI: 10.1016/S0140-
6736(15)01223-4