Biochemical Microvascular Complications of Diabetes

Diabetes mellitus is associated with a spectrum of biochemical microvascular complications that significantly impact various organs and tissues. Chronic hyperglycemia, the hallmark of diabetes, leads to vascular damage through several interconnected pathways, including increased formation of advanced glycation end-products (AGEs), activation of protein kinase C (PKC) isoforms, and oxidative stress. These processes contribute to endothelial [...]