Release Date: 2024-06-12
What Is Immunotherapy and History of Immunotherapy in Cancers
Yusuf Hekimoglu (Author), Orhan Ayyildiz (Author)
Release Date: 2024-06-12
Immunotherapy, a transformative cancer treatment, harnesses the immune system’s inherent ability to combat neoplastic cells. Ancient medicine hinted at immunological principles, recognizing natural disease resistance and the body’s defensive capabilities. Over time, the understanding of the immune system evolved, with key contributions from early thinkers like Ibn Sina and later scientific pioneers like Ilya Mechnikov. [...]
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| Work Type | Book Chapter |
|---|---|
| Published in | Immunotherapy in Human Cancers |
| First Page | 1 |
| Last Page | 10 |
| DOI | https://doi.org/10.69860/nobel.9786053359388.1 |
| Page Count | 10 |
| Copyright Holder | Nobel Tıp Kitabevleri |
| License | https://nobelpub.com/publish-with-us/copyright-and-licensing |
The immune system, comprising innate and adaptive components, is vital in defending against pathogens and regulating cell proliferation, including cancerous cells. The concept of immune surveillance highlights the immune system’s role in preventing cancer development.
Modern immunotherapy includes several approaches: monoclonal antibodies target specific proteins on cancer cells to mark them for destruction; cancer vaccines prevent virus-related cancers like HPV and hepatitis B; adoptive cell therapy, including CAR T-cell and TIL therapies, enhances patients’ immune cells to fight cancer; checkpoint inhibitors block proteins that allow cancer cells to evade the immune response; and oncolytic virotherapy uses engineered viruses to destroy cancer cells and stimulate the immune response.
These therapies, based on profound immunological insights, represent a significant advancement in oncology, offering new hope for patients by leveraging the immune system’s power to combat cancer.
Yusuf Hekimoglu (Author)
Assistant Professor, Dicle University
https://orcid.org/0000-0002-6838-9580
3Yusuf HEKİMOĞLU MD, Internal Medicine Education: • Tishreen University, Syria 2009-2015; Bachelor’s in Medicine. • Dicle university, Türkiye 2021- continues; Internal Medicine. Work experience: • Health Officer; Save the Children International and WELTHUNGERHILFE; Mardin and Antakya, Türkiye 2016-2017 • Physician, Family doctor; Mardin KIZILTEPE 2018-2021 • Resident Doctor, Dicle University Hospitals, Diyarbakır, Türkiye 2021- continues.
Orhan Ayyildiz (Author)
MD, Professor, Dicle University
https://orcid.org/0000-0001-5673-8408
3Orhan Ayyıldız MD,Professor of Internal Medicine and Hematology Education:
· Istanbul University Cerrahpasa Medical faculty, Istanbul , Türkiye 1984-1990.
· Dicle University,Medical faculty Inernal Medicine specialist, Diyarbakir Türkiye , 1990-1994
· Dicle University,Medical faculty hematology specialist, Diyarbakir Türkiye,1994-2000
· Dicle University,Medical faculty Assoc.Prof of Internal medicine, Diyarbakir, Türkiye , 1998
· Dicle University,Medical faculty Prof of Internal Medicine , Diyarbakir Türkiye , 2004-
Orhan Ayyildiz is working now in Dicle University medical faculty department of internal medicine and hematolgy. His interest about all of hematological benign and malign diseases. Also he is a chief of hematology and HLA typing laboratory and chief of apheresis unit more than 30 years. In his clinic more than hundreds of patients transplanted for autologous stem cell transplantation. He is a chief of transfusion comitee of Blood banking of Dicle Medicine faculty. He educated more than thousands of medicine students and more than hundreds resident asistant of internal medicine and hematolgy in Dicle university.
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