Nutrition in the Prevention and Treatment of Endometriosis

Release Date:

Endometriosis is a complex and often debilitating gynecological disorder characterized by the presence of endometrial-like tissue outside the uterus. While the exact cause of endometriosis remains unclear, emerging research suggests that dietary factors may play a significant role in both its development and management.Endometriosis involves a complex, chronic inflammatory process that coincides with the spread [...]

Media Type
    Buy from

    Price may vary by retailers

    Work TypeBook Chapter
    Published inObstetrics & Gynecology and Nutrition
    First Page89
    Last Page98
    DOIhttps://doi.org/10.69860/nobel.9786053359494.7
    Page Count10
    Copyright HolderNobel Tıp Kitabevleri
    Licensehttps://nobelpub.com/publish-with-us/copyright-and-licensing
    Endometriosis is a complex and often debilitating gynecological disorder characterized by the presence of endometrial-like tissue outside the uterus. While the exact cause of endometriosis remains unclear, emerging research suggests that dietary factors may play a significant role in both its development and management.Endometriosis involves a complex, chronic inflammatory process that coincides with the spread of endometriotic lesions into the peritoneum, characterized by proliferation, vascularization, and peritoneal invasion. As a result, there is considerable current interest and ongoing research into the potential for creating an anti-inflammatory response through appropriate nutrition, and understanding how this nutritional support may impact endometriosis.

    Nazenin Balkan (Author)
    MD, Siirt Education and Research Hospital
    https://orcid.org/0009-0002-6830-2948
    3Dr. Nazenin Balkan completed her bachelor’s degree at Dıcle University, School of Medicine in 2019, She worked from as a general practitioner emergency department in the provinces of Diyarbakır. She completed her specialization in obstetrics and gynecology at Dicle University in 2023. She is currently working as a specialist physician at Siirt State Hospital. Nazenin Balkan, MD, Obstetrician and Gynecologist ORCID: 0009-0002-6830-2948 Institution Siirt State Hospital Siirt, Turkey

    • Olive DL, Pritts EA. Treatment of endometriosis. N Engl J Med 2001; 345:266.

    • Sampson JA: Peritoneal endometriosis due to the menstrual dissemination of endometrial tissue into the peritoneal cavity. American Journal of Obstetrics & Gynecology. 1927; 14(4): 422–469.

    • Brosens I, Benagiano G: Is neonatal uterine bleeding involved in the pathogenesis of endometriosis as a source of stem cells? Fertil Steril. 2013; 100(3): 622–3.

    • Iwanoff N. Dusiges cystenhaltiges uterusfibromyom compliciert durch sarcom und carcinom. (Adenofibromyoma cysticum sarcomatodes carcinomatosum) Monatsch Geburtshilfe Gynakol. 1898; 7:295–300.

    • Russell W. Aberrant portions of the mullerian duct found in an ovary. Ovarian cysts of mullerian origin. Bull Johns Hopkins Hosp. 1899; 10:8.

    • Sasson IE, Taylor HS. Stem cells and the pathogenesis of endometriosis. Ann N Y Acad Sci. 2008; 1127:106–15

    • Pascoal E., Wessels J.M., Aas-Eng M.K., et.al. Strengths and limitations of diagnostic tools for endometriosis and relevance in diagnostic test accuracy research. Ultrasound Obstet Gynecol 2022 Mar 1; Epub ahead of print.

    • Guerriero S, Mais V, Ajossa S, et al.: The role of endovaginal ultrasound in differentiating endometriomas from other ovarian cysts. Clin Exp Obstet Gynecol. 1995; 22(1): 20–2

    • Guerriero S, Ajossa S, Minguez JA, et al.: Accuracy of transvaginal ultrasound for diagnosis of deep endometriosis in uterosacral ligaments, rectovaginal septum, vagina and bladder: Systematic review and meta-analysis. Ultrasound Obstet Gynecol. 2015; 46(5): 534–45

    • Dunselman GA, Vermeulen N, Becker C, et al.: ESHRE guideline: management of women with endometriosis. Hum Reprod. 2014; 29(3): 400–12.

    • Casper RF: Progestin-only pills may be a better first-line treatment for endometriosis than combined estrogen-progestin contraceptive pills. Fertil Steril. 2017; 107(3): 533–6.

    • A Study of the Histopathological Changes within Ectopic Endometrial Tissue, in Subjects with Known Pelvic Endometriosis Following Treatment with Ulipristal Acetate, a Selective Progesterone Receptor Modulator (SPRM)

    • Chavarro JE, Rich-Edwards JW, Rosner BA, Willett WC. Use of multivitamins, intake of B vitamins, and risk of ovulatory infertility. Fertil Steril 2008;89: 668–76.

    • Gokhale LB. Curative treatment of primary (spasmodic) dysmenorrheal. Indian J Med Res 1996; 103:227–31.

    • Traber MG, Packer L. Vitamin E: beyond antioxidant function. Am J Clin Nutr 1995; 62:1501S–9.

    • Rayman MP. The importance of selenium to human health. The Lancet 2000; 356:233–41.

    • Colonese F, Laganà AS, Colonese E, et al. The pleiotropic effects of vitamin D in gynaecological and obstetric diseases: an overview on a hot topic. Biomed Res Int 2015; 2015: 986281.

    • Yamamoto A, Harris HR, Vitonis AF, et al. A prospective cohort study of meat and fish consumption and endometriosis risk. Am J Obstet Gynecol. 2018; 219: 178.e1-178.e10.

    • Jurkiewicz-Przondziono J, Lemm M, Kwiatkowska-Pamuła A, et al. Influence of diet on the risk of developing endometriosis. Ginekol Pol 2017; 88: 96-102

    • Chiofalo B, Laganà AS, Palmara V, et al. Fasting as possible complementary approach for polycystic ovary syndrome: hope or hype? Med Hypotheses 2017; 105: 1-3.

    • Habib N, Buzzaccarini G, Centini G, et al. Impact of lifestyle and diet on endometriosis: a fresh look to a busy corner. Prz Menopauzalny. 2022 Jun;21(2):124-132

    • Marziali M, Venza M, Lazzaro S, et al. Gluten-free diet: a new strategy for management of painful endometriosis related symptoms? Minerva Chir 2012; 67: 499-504.

    • Bedaiwy MA, Falcone T, Sharma RK, et al. Prediction of endometriosis with serum and peritoneal fluid markers: a prospective controlled trial. Hum Reprod Oxf Engl 2002; 17: 426-431.

    • Heard ME, Melnyk SB, Simmen FA, et al. High-Fat diet promotion of endometriosis in an immunocompetent mouse model is associated with altered peripheral and ectopic lesion redox and inflammatory status. Endocrinology 2016; 157: 2870-2882.

    Share This Chapter!