Release Date: 2024-06-10

F-18 FDG PET/CT- 1: Basic Principles of Imaging

Fatih Guzel (Author)

Release Date: 2024-06-10

Positron Emission Tomography (PET) is a non-invasive diagnostic method that provides tomographic images by measuring the three-dimensional distribution of pharmaceuticals labeled with positron-emitting radionuclides and provides some quantitative parameters about the metabolic activity or receptor expressions of target tissues. In this way, PET allows the evaluation of biochemical and functional processes. As it is known, [...]

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    Work TypeBook Chapter
    Published inThe Radiology of Cancer
    First Page453
    Last Page459
    DOIhttps://doi.org/10.69860/nobel.9786053359364.28
    Page Count7
    Copyright HolderNobel Tıp Kitabevleri
    Licensehttps://nobelpub.com/publish-with-us/copyright-and-licensing
    Positron Emission Tomography (PET) is a non-invasive diagnostic method that provides tomographic images by measuring the three-dimensional distribution of pharmaceuticals labeled with positron-emitting radionuclides and provides some quantitative parameters about the metabolic activity or receptor expressions of target tissues. In this way, PET allows the evaluation of biochemical and functional processes. As it is known, in malignant cells, glucose metabolism increases and as a result, an increase in FDG uptake is observed.

    Fatih Guzel (Author)
    Dicle University
    https://orcid.org/0000-0002-8571-3418
    3Dr. Fatih Güzel graduated from Dicle University Faculty of Medicine in 2018. He then worked at Silvan District Health Directorate. In 2020, he started working as a research assistant in Dicle University Medical Faculty, Department of Nuclear Medicine. Dr. Güzel has been involved in many research projects. He also actively participated in many national congresses. Dr. Güzel has been working as a specialist physician at Gazi Yaşargil Education Research Hospital since 2024 and continues to contribute to academic studies.

    • Boellaard, R., Delgado-Bolton, R., Oyen, W. J., Giammarile, F., et al. (2015). FDG PET/CT: EANM procedure guidelines for tumour imaging: version 2.0. European journal of nuclear medicine and molecular imaging, 42, 328-354.

    • Jones, T., & Townsend, D. (2017). History and future technical innovation in positron emission tomography. Journal of Medical Imaging, 4(1), 011013-011013.

    • Soydal, Ç., Burak, Z., Uçmak, G., Bozkurt, M. F., Atasever, T., et al. (2020). F-18 FDG PET/BT Onkolojik Uygulama Kılavuzu. Nucl Med Semin, 6, 339-357.

    • Shukla, A. K., Kumar, U. (2006). Positron emission tomography: An overview. Journal of medical physics, 31(1), 13-21.

    • Sezgin, C., Parlak, Y., Mütevelizade, G., Gümüşer, G., et al. (2020). FDG PET Görüntülemelerin Kantitatif Değerlendirilmesi. Celal Bayar Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi, 8(1), 169-173.

    • Adams, M. C., Turkington, T. G., Wilson, J. M., et al. (2010). A systematic review of the factors affecting accuracy of SUV measurements. American Journal of Roentgenology, 195(2), 310-320.

    • Surasi, D. S., Bhambhvani, P., Baldwin, J. A., Almodovar, S. Et al. (2014). 18F-FDG PET and PET/CT patient preparation: a review of the literature. Journal of nuclear medicine technology, 42(1), 5-13.

    • ICRP. Radiation dose to patients from radiopharmaceuticals. Addendum 3 to ICRP Publication 53. ICRP Publication 106.Approved by the Commission in October 2007. Ann ICRP. 2008;38(1-2):1–197.

    • Hicks, R. J., Binns, D., Stabin, M. G. (2001). Pattern of uptake and excretion of 18F-FDG in the lactating breast. Journal of Nuclear Medicine, 42(8), 1238-1242.

    • Weber, W. A., Wieder, H. (2006). Monitoring chemotherapy and radiotherapy of solid tumors. European journal of nuclear medicine and molecular imaging, 33, 27-37.

    • Parlak, Y., Göksoy, D., Mütevelizade, G., Gümüşer, G., & Sayit, E. (2019). Baseline SUV Range for Liver and Blood Pool in Patients Undergoing F-18 Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography. Istanbul Medical Journal= Istanbul Tip Dergisi, 20(5), 431.

    • Thie, J. A. (2004). Understanding the standardized uptake value, its methods, and implications for usage. Journal of Nuclear Medicine, 45(9), 1431-1434.

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