Release Date: 2024-06-07

Genus Dactylorhiza: a Phytochemical and Pharmacological Overview

Release Date: 2024-06-07

This chapter overviewed the applications and various pharmacological properties of the species of Dactylorhiza in traditional and modern medicine in the world and Türkiye. Upon analyzing all research findings on Dactylorhiza species, it was found that most data were gathered concerning its anti-diabetic and antioxidant properties.

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    Work TypeBook Chapter
    Published inNatural Antioxidants and in Vitro Antioxidant Assays
    First Page163
    Last Page177
    DOIhttps://doi.org/10.69860/nobel.9786053359333.7
    Page Count15
    Copyright HolderNobel Tıp Kitabevleri
    Licensehttps://nobelpub.com/publish-with-us/copyright-and-licensing
    This chapter overviewed the applications and various pharmacological properties of the species of Dactylorhiza in traditional and modern medicine in the world and Türkiye. Upon analyzing all research findings on Dactylorhiza species, it was found that most data were gathered concerning its anti-diabetic and antioxidant properties.

    Hatice Kiziltas (Author)
    PhD, Assoc. Prof. Dr., Van Yuzuncu Yil University
    https://orcid.org/0000-0002-0833-3358
    3Assoc. Dr. (Biochemist)

    • Păltinean R, Ielciu I, Vlase L, Mocan A, Gheldiu AM, Babotă M, et al. Histo-anatomical researches, polyphenolic profile and biological activities of the aerial parts and tubers of dactylorhiza maculata L. SoÓ. (orchidaceae). Farmacia. 2017;65(6):837–42.

    • Boissier E. Volume 5 (Orchidaceae). In: Flora Orientalis: Monocotyledoneae. Genevae Botany; 1884. p. 421–2.

    • Chase MW, Cameron KM, Freudenstein J V., Pridgeon AM, Salazar G, van den Berg C, et al. An updated classification of Orchidaceae. Bot J Linn Soc. 2015;177(2):151–74.

    • Christenhusz MJM, Byng JW. The number of known plants species in the world and its annual increase. Phytotaxa. 2016;261(3):201–17.

    • Dorjey K, Maurya AK, Sinha D. Dactylorhiza hatagirea (D. Doon) Soo, an important medicinal herb of the Himalaya and urgent need for its conservation-A review. Indian J Nat Prod Resour. 2022;13(3):265–73.

    • Bozkir B, Acet T, Özcan K. Investigation of the effects of different extraction methods on some biological activities of Dactylorhiza romana subsp. georgica (Klinge) Soó ex Renz & Taubenheim. South African J Bot. 2022;149:347–54.

    • Devos N, Raspé O, Oh SH, Tyteca D, Jacquemart AL. The evolution of Dactylorhiza (Orchidaceae) allotetraploid complex: Insights from nrDNA sequences and cpDNA PCR-RFLP data. Mol Phylogenet Evol. 2006;38(3):767–78.

    • Karel K. Türkiye Orkideleri Botanik Özellikleri, Ekolojik İstekleri, Doğal Yayılış Alanları, Yaşam Tehtitleri, Koruma Önlemleri. First edit. Alper Hüseyin ÇOLAK, editor. Rota Yayınları; 2009. 848 p.

    • Daşkın R, Özer Y, Kaynak G. A new record for the flora of Turkey. Turk J Botany. 1997;21(4):247–9.

    • Yıldırım Çelik S. Identification of protease enzyme in salep orchid tubers, and investigation of the usability of the enzyme in casein and gluten hydrolysis. Int Food Res J. 2021;28(4):672–81.

    • Sezik E. Turkish Orchids and Salep. Acta Pharm Turc. 2002;44:151–7.

    • Erzurumlu GS, Doran İ. Türki̇ye’de salep orki̇deleri̇ ve salep kültürü. Harran Üniverisitesi Ziraat Fakültesi Derg. 2011;15(1):29–34.

    • Tekinşen KK, Güner A. Chemical composition and physicochemical properties of tubera salep produced from some Orchidaceae species. Food Chem. 2010;121(2):468–71.

    • Sukhikh S, Asyakina L, Korobenkov M, Skrypnik L, Pungin A, Ivanova S, et al. Chemical composition and content of biologically active substances found in cotinus coggygria, dactylorhiza maculata, platanthera chlorantha growing in various territories. Plants. 2021;10(12).

    • Sukhikh S, Noskova S, Ivanova S, Skrypnik L, Pungin A, Ulrikh E, et al. Study of the Properties of In Vitro Dactylorhiza maculata ( L .) So ó ( Family Orchidaceae ) Extracts. Plants. 2021;10(1330):1–12.

    • Kiziltas H, Goren AC, Alwasel SH, Gulcin İ. Sahlep (Dactylorhiza osmanica): Phytochemical Analyses by LC-HRMS, Molecular Docking, Antioxidant Activity, and Enzyme Inhibition Profiles. Molecules. 2022;27(20).

    • Haruhisa K, Ei-İchiKaneko., Tsuyoshi T. NII-Electronic Library Service. Chem Pharm Bull [Internet]. 1999;47(11):1618–25. Available from: http://www.mendeley.com/research/geology-volcanic-history-eruptive-style-yakedake-volcano-group-central-japan/

    • Shivani Vishwakarma SK. An Overview of Phytochemical Identification of Secondary Metabolites of Medicinal Plant Dactylorhiza Hatagirea. Asian J Pharm Res Dev. 2021;9(2):65–9.

    • Dhiman N, Sharma NK, Thapa P, Sharma I, Kumar Swarnkar M, Chawla A, et al. De novo transcriptome provides insights into the growth behaviour and resveratrol and trans-stilbenes biosynthesis in Dactylorhiza hatagirea - An endangered alpine terrestrial orchid of western Himalaya. Sci Rep. 2019;9(1):1–11.

    • Wani IA, Kumar V, Verma S, Jan AT, Rather IA. Dactylorhiza hatagirea (D. don) soo: A critically endangered perennial orchid from the north-west himalayas. Plants. 2020;9(12):1–17.

    • Mecca M, Racioppi R, Romano VA, Viggiani L, Lorenz R, D’Auria M. Volatile Organic Compounds in Dactylorhiza Species. Compounds. 2022;2(2):121–30.

    • Kızıltaş H, Ekin S, Yıldız D, Pınar SM. Evaluation of Antioxidant Properties, Trace Element and Mineral Composition of Dactylorhiza umbrosa (Kar. & Kir.) Nevski (Orchidaceae). Iğdır Üniversitesi Fen Bilim Enstitüsü Derg. 2019;9(4):2148–56.

    • Thakur M, Dixit VK. Aphrodisiac activity of Dactylorhiza hatagirea (D.Don) Soo in male albino rats. Evidence-based Complement Altern Med. 2007;4(SUPPL. 1):29–31.

    • Thakur M, Dixit VK. Effect of some vajikaran herbs on pendiculation activities and in vitro sperm count in male. Sex Disabil. 2007;25(4):203–7.

    • Alsawalha M, Al-subaei AM, Al-jindan RY, Bolla SR, Sen D, Balakrishna JP, et al. Anti ‑ diabetic Activities of Dactylorhiza hatagirea Leaf Extract in 3T3 ‑ L1 Cell Line Model. Pharmacogn Mag. 2019;15(64):212–7.

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