Newborn Screening for Spinal Muscular Atrophy

Spinal muscular atrophy (SMA) is a progressive neuromuscular disorder caused by the loss of motor neurons, leading to muscle weakness and atrophy. It has a global incidence of approximately 1 in 6,000 to 11,000 live births and is a significant hereditary cause of infant mortality. SMA is classified into five subtypes based on the age [...]