Genetic Research in Alzheimer’s Disease

Alzheimer’s Disease is classified by age of onset: early-onset (EOAD) before 60-65 years, comprising 5-10% of cases, and late-onset (LOAD) after 60-65 years, accounting for 95%. Familial AD, resulting from single gene mutations, represents a small percentage, with most cases being sporadic and multifactorial. Advancements in Next-Generation Sequencing (NGS) have enabled the identification of numerous [...]