Release Date: 2024-05-28

Alzheimer’s Disease From Molecular Mechanisms to Clinical Practices

Release Date: 2024-05-28

“Alzheimer’s Disease: From Molecular Mechanisms to Clinical Practices” explores the extensive perspective from the molecular foundations to the clinical diagnosis and treatment of Alzheimer’s disease.

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Work TypeEdited Book
Internal ReferenceNBL44
Edition1
DOIhttps://doi.org/10.69860/nobel.9786053359166
ISBN978-605-335-916-6 (PAPERBACK)
LanguageENG
Page Count362
Print Lenghtxvi+346
PlaceIstanbul
Copyright HolderNobel Tıp Kitabevleri
Licensehttps://nobelpub.com/publish-with-us/copyright-and-licensing
BICMJND
BISACMED089000
THEMAMKJD
“Alzheimer’s Disease: From Molecular Mechanisms to Clinical Practices” explores the extensive perspective from the molecular foundations to the clinical diagnosis and treatment of Alzheimer’s disease. The book serves as a fundamental resource for understanding the neurobiological basis and molecular pathogenesis of Alzheimer’s, while also discussing the challenges and opportunities of transitioning from the laboratory to clinical settings. The initial sections of the book comprehensively examine the fundamental molecular characteristics of Alzheimer’s disease; these include the accumulation of amyloid-beta peptide, hyperphosphorylation of tau protein, and how these processes lead to synaptic dysfunction and neuronal death. These chapters provide strategies on how to understand the pathology of the disease at a molecular level and how this knowledge can be translated into clinical practice. Subsequent parts focus on the development and use of biomarkers for the early diagnosis of Alzheimer’s disease. In addition to the role of genetic predispositions, the effects of environmental factors and lifestyle choices on Alzheimer’s disease are discussed, highlighting the multifactorial nature of the disease. In conclusion, this book is a valuable resource for clinicians, researchers, and medical students specializing in the field. It provides essential scientific and practical information necessary for a better understanding and management of Alzheimer’s disease, offering a comprehensive perspective on the integration of molecular mechanisms with clinical applications.
  1. Nervous System, Neurons, and Metabolism (pp. 3-36)
    Dildar Konukoglu
  2. Signal Transmission (pp. 37-76)
    Merve Nur Gecin, Aykut Oruc, Kadriye Yagmur Oruc, Hakki Oktay Seymen
  3. Alzheimer’s Disease and Dementia: Epidemiology, Social and Economic Challenge (pp. 77-92)
    Ani Hande Mete, Canser Boz
  4. Alzheimer’s Disease: Link to Biomolecular Mechanisms and Clinical Pathologies (pp. 93-108)
    Erdinc Dursun, Duygu Gezen Ak
  5. Clinical Diagnosis of Alzheimer’s Disease (pp. 109-134)
    Zeynep Ece Kaya Gulec, Melda Bozluolcay
  6. Biomarkers in Alzheimer’s Disease: Structure and Assays (pp. 135-152)
    Erdinc Dursun, Busra Sengul Yediel, Duygu Gezen Ak, Zuhal Yurttas, Tugay Camoglu, Merve Alaylioglu
  7. Experimental Models of Alzheimer’s Disease (pp. 153-174)
    Alev Meltem Ercan
  8. Genetic Research in Alzheimer’s Disease (pp. 175-187)
    Fatih Tepgec, Zehra Oya Uyguner
  9. Metabolomics in Alzheimer’s Disease (pp. 189-208)
    Asuman Gedikbasi
  10. Alzheimer’s Disease and Diabetes Mellitus: Molecular Links (pp. 209-257)
    Dildar Konukoglu
  11. Alzheimer’s Disease and Obesity (pp. 259-274)
    Solmaz Susam, Nevin Ilhan
  12. Relationship Between Dyslipidemia and Alzheimer’s Disease (pp. 275-297)
    Mine Kucur, Ibrahim Murat Bolayirli
  13. Association of Infections with Alzheimer’s Disease (pp. 299-328)
    Huseyin Yilmaz
  14. Medicolegal Aspect of Alzheimer’s Disease and Dementia (pp. 329-341)
    Filiz Ekim Cevik, Dursun Kirbas

Dildar Konukoglu (Editor)
Professor, Istanbul Cerrahpasa University
https://orcid.org/0000-0002-6095-264X
3Dildar Konukoğlu was born on April 18, 1963, in Istanbul. She obtained her medical degree from Ege University in 1987. In 1991, she attained the rank of specialist in Medical Biochemistry. In 1995, she was promoted to the position of associate professor of medical biochemistry and, in 2000, to the rank of professor. She is currently a member of the faculty at the Department of Medical Biochemistry at Cerrahpaşa Medical Faculty and serves as the director of the Medical Biochemistry Laboratory at Cerrahpaşa Medical Faculty Hospital. She also holds the role of Chairman of the Environmental Management Unit of Cerrahpaşa Medical Faculty. Furthermore, she serves as the director of the Istanbul University-Cerrahpaşa Clinical Research Excellence Application and Research Center. She has participated in numerous commissions within the Ministry of Health and currently serves as a member of the Medical Specialty Education Commission. She served as the Head of the Department of Medical Biochemistry from 2016 to 2019. She has advised on 10 postgraduate test projects and participated in 25 completed projects as an executive or researcher. She has published a total of 180 original articles, 130 of which are international. Her WOS H index is 25. She has authored or edited 64 books and has delivered lectures and organized courses at numerous congresses and symposia. Her primary clinical research interests include endocrinology, neurology, nephrology, neonatal metabolic diseases, obesity, and atherosclerosis-related biomolecular mechanisms and pathways. Since 2016, she has served as the Chairman of the Board of Directors of the Association of Clinical Biochemists. She is the Editor-in-Chief of the International Journal of Medical Biochemistry. She is married and has a son.

reviews

3 reviews for Alzheimer’s Disease From Molecular Mechanisms to Clinical Practices

  1. Brian

    This book is great for a quick review. Helps me a lot at work !

  2. Dr. Ramdayal Pandey

    A wonderful book. Highly recommend.

  3. Dr. Henry Roberts

    This publication is one of the best books for doctors in terms of its positive approach to Alzheimer’s and its variety of treatments.

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