Release Date: 2024-06-12

Immunotherapy in Human Cancers

Orhan Ayyildiz (Editor), Emin Kaplan (Editor)

Release Date: 2024-06-12

In ancient medicine, many scientists have mentioned that the human body has its own mechanisms to defend against diseases and achieve either a cure or the symptomatic response. In the 5th century B.C., the ancient Greeks noted that patients who survived the plague disease were somehow immune to it. Ibn Sina, in his book 'The [...]

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Work TypeEdited Book
Internal ReferenceNBL62
Edition1
DOIhttps://doi.org/10.69860/nobel.9786053359388
ISBN978-605-335-938-8 (PDF)
LanguageENG
Page Count248
Print Lenghtx+238
PlaceIstanbul
Copyright HolderNobel Tıp Kitabevleri
Licensehttps://nobelpub.com/publish-with-us/copyright-and-licensing
BICMJCL
BISACMED062000
THEMAMJCL
In ancient medicine, many scientists have mentioned that the human body has its own mechanisms to defend against diseases and achieve either a cure or the symptomatic response. In the 5th century B.C., the ancient Greeks noted that patients who survived the plague disease were somehow immune to it. Ibn Sina, in his book ’The Canon of Medicine,’ describes the basics of our immune system with general concepts. Ibn Sina had mentioned that the human body has its own defense power and called it ’Quatu-almudafat’ in the Arabic language. Not only the contagious behavior of some diseases (person to person) and the distribution nature of them (through water or solids), but also, he mentioned or believed that these contagious diseases need 40 days to be under control and limit the spread of infections. However, the term ’immunology’ was much later coined by the Russian biologist Ilya Ilyich Mechnikov, who received the Nobel Prize in 1908 with Paul Ehrlich for their study and work on immunity. There have been rapid advances in immunology, as in every field of science in the 20th and 21st centuries. Developments in biology, microbiology, drug production and advances in many fields have led to the recognition of cell antigenicity, the definition of foreign antigen and antibody relationships, and finally the treatments we call Immunotherapy, in which humoral and cellular components have been developed today, as well as treatments with antibodies alone or antibody drugs, antibody toxins, antibody radioactive congucation. In addition cellular therapy mediated by T cells and NK cells (such as CAR-T cell, CAR-NK, LAK) have been developed.
Today and in the near future, immune therapies seem to play a role in many diseases other than cancer. Immune therapies alone or with drug/toxin conjugates are promising in cancer treatments and have led and will lead to very long-term survival in some cancers.
This book, which is the book on immune therapies in cancer, has been prepared by doctors who are experts in the field of immune therapies in some hematological and non-hematological cancers. Information on the subject is the responsibility of the author. We hope that this book, in which you will read many innovations, will be useful.
  1. What Is Immunotherapy and History of Immunotherapy in Cancers (pp. 1-10)
    Yusuf Hekimoglu, Orhan Ayyildiz
  2. Types of Immunotherapy, Mechanism of Action and Side Effects (pp. 11-24)
    Sehmus Ertop, Birsen Sahip Yesiralioglu, Hatice Ayag, Muzeyyen Aslaner Ak
  3. Immunotherapy and Immunotherapeutic Drugs (pp. 25-32)
    Hasan Akkoc
  4. Hyperthermia: Causes, Symptoms, Prevention and Treatment (pp. 229-238)
    Omer Isik
  5. Immunotherapy in Gynecologic (Ovary, Endometrium and Servics) Cancer (pp. 219-228)
    Sait Kitapli, Ali Alkan
  6. Immunotherapy in Lung and Thoracic Cancer (pp. 167-186)
    Omer Fatih Olmez, Harun Muglu
  7. Immunotherapy in Brain, Head and Neck Cancer (pp. 151-166)
    Nuriye Ozdemir, Imdat Eroglu, Ozan Yazici
  8. Immunotherapy in Hodgkin Lymphoma (pp. 107-113)
    Ozge Sonmez, Mehmet Sonmez
  9. Immunotherapy in Chronic Leukemias (pp. 91-106)
    Esin Oguz Kozan, Eyup Naci Tiftik
  10. Immunotherapy in Acute Leukemias (pp. 61-89)
    Leylagul Kaynar, Yasemin Ozgur
  11. Immunotherapy in Benign Hematological Diseases (pp. 49-60)
    Cihan Ural
  12. Immunotherapy in Breast Cancer (pp. 187-204)
    Baran Akagunduz, Mehmet Cihan Icli
  13. Immunotherapy in Gastro-Esophageal Cancers (pp. 205-218)
    Yasin Sezgin, Mahmut Kara
  14. Immunotherapy in Hematological Malignancy (pp. 33-48)
    Sehmus Ertop, Birsen Sahip Yesiralioglu, Hatice Ayag, Muzeyyen Aslaner Ak
  15. Immunothearpy for the Treatment of Multiple Myeloma (pp. 115-139)
    Ugur Hatipoglu, Turgay Ulas, Nazik Okumus
  16. Immunotherapy in Solid Tumors (pp. 141-149)
    Zeynep Oruc, Ziya Kalkan

Orhan Ayyildiz (Editor)
MD, Professor, Dicle University
https://orcid.org/0000-0001-5673-8408
3Orhan Ayyıldız MD,Professor of Internal Medicine and Hematology Education: · Istanbul University Cerrahpasa Medical faculty, Istanbul , Türkiye 1984-1990. · Dicle University,Medical faculty Inernal Medicine specialist, Diyarbakir Türkiye , 1990-1994 · Dicle University,Medical faculty hematology specialist, Diyarbakir Türkiye,1994-2000 · Dicle University,Medical faculty Assoc.Prof of Internal medicine, Diyarbakir, Türkiye , 1998 · Dicle University,Medical faculty Prof of Internal Medicine , Diyarbakir Türkiye , 2004- Orhan Ayyildiz is working now in Dicle University medical faculty department of internal medicine and hematolgy. His interest about all of hematological benign and malign diseases. Also he is a chief of hematology and HLA typing laboratory and chief of apheresis unit more than 30 years. In his clinic more than hundreds of patients transplanted for autologous stem cell transplantation. He is a chief of transfusion comitee of Blood banking of Dicle Medicine faculty. He educated more than thousands of medicine students and more than hundreds resident asistant of internal medicine and hematolgy in Dicle university.

Muhammet Ali Kaplan (Editor)
MD, Professor, Dicle University
https://orcid.org/0000-0003-0882-0524
3Muhammet Ali Kaplan, MD, Professor Education. Istanbul university medicine faculty (1996-2002) Dicle University Internal medicine (2002-2008) Dicle University Medical Oncology (2009-)

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1 review for Immunotherapy in Human Cancers

  1. Dr. Terrence McGarty

    A great source of information on immunotherapy in human cancers.

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