Extrapulmonary tuberculosis refers to the manifestation of tuberculosis outside the lungs, caused by the dissemination of Mycobacterium tuberculosis through the bloodstream or lymphatic system. EPTB can affect virtually any organ, leading to a wide array of clinical presentations. Common forms include lymphatic tuberculosis, which involves swollen and often painful lymph nodes; pleural tuberculosis, characterized by pleural effusion and chest pain; and tuberculous meningitis, presenting with severe headaches, neck stiffness, and neurological symptoms. Other forms include skeletal tuberculosis, genitourinary tuberculosis, and abdominal tuberculosis, each with its own distinct symptoms and diagnostic challenges. Extrapulmonary tuberculosis is more common in individuals with compromised immune systems, such as those with HIV/AIDS. Diagnosing extrapulmonary tuberculosis often requires a combination of clinical suspicion, imaging studies, and microbiological tests. Understanding the diverse manifestations of extrapulmonary tuberculosis is crucial for effective diagnosis, treatment, and management of this complex form of tuberculosis.