Diabetes Mellitus is a significant global health concern characterized by chronic hyperglycemia resulting from insulin secretion or action defects. Its prevalence escalates due to aging populations, urbanization, sedentary lifestyles, and poor diets. The disease manifests primarily as Type 1 (autoimmune destruction of pancreatic beta cells) and Type 2 (insulin resistance with relative deficiency). Complications include cardiovascular diseases and microvascular issues like retinopathy and neuropathy. Management involves lifestyle changes, medications, insulin therapy, and regular monitoring. Addressing diabetes requires comprehensive strategies spanning prevention, early detection, and effective treatment, supported by global initiatives like the WHO’s Diabetes Compact.